Gene Symbol | KRTAP5-9 |
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Entrez Gene | 3846 |
Alt Symbol | KRN1, KRTAP5-1, KRTAP5.9 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 5-9 |
Other Description | UHS KerA|UHS keratin A|keratin, cuticle, ultrahigh sulfur 1|keratin, cuticle, ultrahigh sulphur 1|keratin, ultra high-sulfur matrix protein A|keratin-associated protein 5-9|keratin-associated protein 5.9|ultrahigh sulfur keratin-associated protein 5.9 |
Swissprots | P26371 Q3MIP8 Q14564 |
Accessions | CAA07189 CAA39005 P26371 AB126078 BAD20205 BC069531 AAH69531 BC101744 AAI01745 DB339866 HQ448422 ADQ32902 X63755 CAA45283 NM_005553 NP_005544 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles. {ECO:0000269|PubMed:15144888}. |
KRTAP5-9 CRISPR/Cas9 KO Plasmid (h) - sc-410856 from Santa Cruz Biotechnology
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KRTAP5-9 HDR Plasmid (h) - sc-410856-HDR from Santa Cruz Biotechnology
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KRTAP5-9 Double Nickase Plasmid (h) - sc-410856-NIC from Santa Cruz Biotechnology
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KRTAP5-9 Double Nickase Plasmid (h2) - sc-410856-NIC-2 from Santa Cruz Biotechnology
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KRTAP5-9 CRISPR Activation Plasmid (h) - sc-410856-ACT from Santa Cruz Biotechnology
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KRTAP5-9 CRISPR Activation Plasmid (h2) - sc-410856-ACT-2 from Santa Cruz Biotechnology
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KRTAP5-9 Lentiviral Activation Particles (h) - sc-410856-LAC from Santa Cruz Biotechnology
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KRTAP5-9 Lentiviral Activation Particles (h2) - sc-410856-LAC-2 from Santa Cruz Biotechnology
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KRTAP5-9 siRNA (h) - sc-96496 from Santa Cruz Biotechnology
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KRTAP5-9 shRNA Plasmid (h) - sc-96496-SH from Santa Cruz Biotechnology
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KRTAP5-9 shRNA (h) Lentiviral Particles - sc-96496-V from Santa Cruz Biotechnology
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KRTAP5-1 RNAi - H00387264-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN11489 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11489 from Sigma-Aldrich
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KRTAP5-9 siRNA (Human) - CRH2608 from Cohesion Biosciences
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KRTAP5-9 shRNA Plasmid (Human) - CHH2608 from Cohesion Biosciences
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KRTAP5-9 miRNA 3'UTR clone - MiUTR1H-05529 from Creative biogene
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