ERRFI1

Gene Symbol	ERRFI1
Entrez Gene	54206
Alt Symbol	GENE-33, MIG-6, MIG6, RALT
Species	Human
Gene Type	protein-coding
Description	ERBB receptor feedback inhibitor 1
Other Description	mitogen-inducible gene 6 protein|receptor-associated late transducer
Swissprots	Q9NTG9 Q9UJM3 Q9UD05 B2RDX9
Accessions	AFM52327 EAW71592 EAW71593 EAW71594 Q9UJM3 AJ276373 CAC20426 AK027830 AK096149 BAG53220 AK315718 BAG38076 AL137274 CAB70672 BC012839 BC025337 AAH25337 DB033666 DQ892137 ABM83063 DQ895331 ABM86257 XM_005263477 XP_005263534 XM_006710697 XP_006710760 XM_011541596 XP_011539898 NM_018948 NP_061821
Function	Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:7641805}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with the plasma membrane of basal skin keratinocytes. Translocates into the nucleus of differentiating suprabasal keratinocytes (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ERBB receptor feedback inhibitor 1 (ERRFI1), Human, ELISA Kit - CSB-EL007804HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

ERBB receptor feedback inhibitor 1, ELISA Kit - MBS907410 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human ERRFI1 is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml-2000 pg/ml.

Human ERBB receptor feedback inhibitor 1(ERRFI1) ELISA kit - CSB-EL007804HU from Cusabio Category ELISA Kit Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Human ERBB receptor feedback inhibitor 1 (ERRFI1) ELISA Kit - EKC33627 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Human ERRFI1 ELISA Kit - E013533 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human ERRFI1 is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

ERRFI1 ELISA Kit (Human) (OKCA01230) - OKCA01230 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 7.81 pg/mL Range 31.25 - 2,000 pg/mL

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