Gene Symbol |
CCNK
|
Entrez Gene |
8812
|
Alt Symbol |
CPR4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cyclin K
|
Other Description |
cyclin-K
|
Swissprots |
Q86U16 Q59FT6 Q96B63 O75909 Q9NNY9
|
Accessions |
AAN06829 EAW81668 EAW81669 EAW81670 EAW81671 EAW81672 O75909 AB209373 BAD92610 AK311075 BC015935 AAH15935 BG503760 BM505592 BQ432222 BT006950 AAP35596 BX247958 CAD62298 DQ893538 ABM84464 EU176485 ABW03286 XM_005268154 XP_005268211 XM_011537275 XP_011535577 NM_001099402 NP_001092872 NM_003858
|
Function |
Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). {ECO:0000269|PubMed:10574912, ECO:0000269|PubMed:22012619, ECO:0000269|PubMed:9632813}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:22012619}.
|
Tissue Specificity |
Ubiquitously expressed. Highest levels in testis. {ECO:0000269|PubMed:9632813}.
|