Gene Symbol | CCNK |
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Entrez Gene | 8812 |
Alt Symbol | CPR4 |
Species | Human |
Gene Type | protein-coding |
Description | cyclin K |
Other Description | cyclin-K |
Swissprots | Q86U16 Q59FT6 Q96B63 O75909 Q9NNY9 |
Accessions | AAN06829 EAW81668 EAW81669 EAW81670 EAW81671 EAW81672 O75909 AB209373 BAD92610 AK311075 BC015935 AAH15935 BG503760 BM505592 BQ432222 BT006950 AAP35596 BX247958 CAD62298 DQ893538 ABM84464 EU176485 ABW03286 XM_005268154 XP_005268211 XM_011537275 XP_011535577 NM_001099402 NP_001092872 NM_003858 |
Function | Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). {ECO:0000269|PubMed:10574912, ECO:0000269|PubMed:22012619, ECO:0000269|PubMed:9632813}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22012619}. |
Tissue Specificity | Ubiquitously expressed. Highest levels in testis. {ECO:0000269|PubMed:9632813}. |
cyclin K CRISPR/Cas9 KO Plasmid (h) - sc-405254 from Santa Cruz Biotechnology
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cyclin K HDR Plasmid (h) - sc-405254-HDR from Santa Cruz Biotechnology
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cyclin K Double Nickase Plasmid (h) - sc-405254-NIC from Santa Cruz Biotechnology
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cyclin K Double Nickase Plasmid (h2) - sc-405254-NIC-2 from Santa Cruz Biotechnology
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cyclin K CRISPR Activation Plasmid (h) - sc-405254-ACT from Santa Cruz Biotechnology
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cyclin K CRISPR Activation Plasmid (h2) - sc-405254-ACT-2 from Santa Cruz Biotechnology
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cyclin K Lentiviral Activation Particles (h) - sc-405254-LAC from Santa Cruz Biotechnology
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cyclin K Lentiviral Activation Particles (h2) - sc-405254-LAC-2 from Santa Cruz Biotechnology
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cyclin K siRNA (h) - sc-37600 from Santa Cruz Biotechnology
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cyclin K shRNA Plasmid (h) - sc-37600-SH from Santa Cruz Biotechnology
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cyclin K shRNA (h) Lentiviral Particles - sc-37600-V from Santa Cruz Biotechnology
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CCNK RNAi - H00008812-R01V from Novus Biologicals
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CCNK RNAi - H00008812-R02 from Novus Biologicals
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MISSION® esiRNA - EHU096041 from Sigma-Aldrich
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MISSION® esiRNA - EHU094831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5645 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5645 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06854 from Sigma-Aldrich
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CCNK siRNA (Human) - CRH5810 from Cohesion Biosciences
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CCNK - MBS8203400 from MyBioSource
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shRNA set against Human CCNK (NM_001099402.1) - SHH257993 from Creative biogene
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Human CCNK siRNA - orb266312 from Biorbyt
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CCNK shRNA Plasmid (Human) - CHH5810 from Cohesion Biosciences
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CCNK miRNA 3'UTR clone - MiUTR3H-06064 from Creative biogene
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