Gene Symbol | IL6 |
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Entrez Gene | 102138971 |
Alt Symbol | IL-6 |
Species | Monkey |
Gene Type | protein-coding |
Description | interleukin 6 (interferon, beta 2) |
Other Description | hypothetical protein|interleukin-6 |
Swissprots | P79341 |
Accessions | EHH52277 P79341 AB000554 BAA19148 XM_005550000 XP_005550057 XM_005550001 XP_005550058 XM_005550002 XP_005550059 XM_005550003 XP_005550060 |
Function | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD), Rheumatoid arthritis, Toll-like receptor signaling pathway, Jak-STAT signaling pathway |
Anti-IL6 antibody [5E1] - ab8472 from Abcam
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IL6 antibody [MP5-32C11] - GTX27376 from GeneTex
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BD Pharmingen™ PE Rat Anti-Human IL-6 - 551473 from BD Biosciences
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IL6 / IL-6 Antibody, Rabbit PAb - 90197-RP01-200 from Sino Biological
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IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified - 90197-RP02-50 from Sino Biological
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Mouse anti-Monkey IL6 Monoclonal antibody, clone 6F2 - DCABH-10083 from Creative Diagnostics
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Rat anti-IL6 Monoclonal antibody [clone OR7-44E23] - DMABT-Z59728 from Creative Diagnostics
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Cynomolgus Monkey IL-6 Polyclonal Antibody - KP1167Y-100 from Kingfisher Biotech
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Cynomolgus Monkey IL-6 Polyclonal Antibody - Biotinylated - KPB1168Y-050 from Kingfisher Biotech
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IL6 antibody - orb171286 from Biorbyt
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Interleukin 6 - ARB-64227 from Nordic BioSite
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IL6 Antibody (OACD00135) - OACD00135 from Aviva Systems Biology
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