| Gene Symbol |
MIS18BP1
|
| Entrez Gene |
55320
|
| Alt Symbol |
C14orf106, HSA242977, KNL2, M18BP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MIS18 binding protein 1
|
| Other Description |
P243|hsKNL-2|kinetochore null 2 homolog|kinetochore-associated protein KNL-2 homolog|mis18-binding protein 1|putative protein p243 which interacts with transcription factor Sp1
|
| Swissprots |
D3DSA7 Q96PY4 Q86V14 Q6P0N0 Q9Y4X9 Q9NUR5
|
| Accessions |
EAW65777 EAW65778 EAW65779 EAW65780 Q6P0N0 AB067490 BAB67796 AJ242977 CAB45134 AK002048 AW971491 BC051885 AAH51885 BC065544 AAH65544 XM_005267833 XP_005267890 XM_011536923 XP_011535225 XR_943484 XR_943485 NM_018353 NP_060823
|
| Function |
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. {ECO:0000269|PubMed:17199038, ECO:0000269|PubMed:17339379}.
|
| Subcellular Location |
Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
|