Gene Symbol | MIS18BP1 |
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Entrez Gene | 55320 |
Alt Symbol | C14orf106, HSA242977, KNL2, M18BP1 |
Species | Human |
Gene Type | protein-coding |
Description | MIS18 binding protein 1 |
Other Description | P243|hsKNL-2|kinetochore null 2 homolog|kinetochore-associated protein KNL-2 homolog|mis18-binding protein 1|putative protein p243 which interacts with transcription factor Sp1 |
Swissprots | D3DSA7 Q96PY4 Q86V14 Q6P0N0 Q9Y4X9 Q9NUR5 |
Accessions | EAW65777 EAW65778 EAW65779 EAW65780 Q6P0N0 AB067490 BAB67796 AJ242977 CAB45134 AK002048 AW971491 BC051885 AAH51885 BC065544 AAH65544 XM_005267833 XP_005267890 XM_011536923 XP_011535225 XR_943484 XR_943485 NM_018353 NP_060823 |
Function | Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. {ECO:0000269|PubMed:17199038, ECO:0000269|PubMed:17339379}. |
Subcellular Location | Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin. |
KNL2 CRISPR/Cas9 KO Plasmid (h) - sc-405517 from Santa Cruz Biotechnology
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KNL2 HDR Plasmid (h) - sc-405517-HDR from Santa Cruz Biotechnology
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KNL2 Double Nickase Plasmid (h) - sc-405517-NIC from Santa Cruz Biotechnology
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KNL2 Double Nickase Plasmid (h2) - sc-405517-NIC-2 from Santa Cruz Biotechnology
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KNL2 CRISPR Activation Plasmid (h) - sc-405517-ACT from Santa Cruz Biotechnology
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KNL2 CRISPR Activation Plasmid (h2) - sc-405517-ACT-2 from Santa Cruz Biotechnology
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KNL2 Lentiviral Activation Particles (h) - sc-405517-LAC from Santa Cruz Biotechnology
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KNL2 Lentiviral Activation Particles (h2) - sc-405517-LAC-2 from Santa Cruz Biotechnology
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KNL2 siRNA (h) - sc-92201 from Santa Cruz Biotechnology
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KNL2 shRNA Plasmid (h) - sc-92201-SH from Santa Cruz Biotechnology
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KNL2 shRNA (h) Lentiviral Particles - sc-92201-V from Santa Cruz Biotechnology
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KNL-2 RNAi - H00055320-R01 from Novus Biologicals
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MISSION® esiRNA - EHU060731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4310 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4310 from Sigma-Aldrich
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MIS18BP1 siRNA (Human) - CRJ0652 from Cohesion Biosciences
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shRNA set against Human MIS18BP1 (NM_018353.4) - SHH342187 from Creative biogene
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Human MIS18BP1 siRNA - orb271153 from Biorbyt
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MIS18BP1 shRNA Plasmid (Human) - CHJ0652 from Cohesion Biosciences
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MIS18BP1 miRNA 3'UTR clone - MiUTR3H-13886 from Creative biogene
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