CAPN2

Gene Symbol CAPN2
Entrez Gene 824
Alt Symbol CANP2, CANPL2, CANPml, mCANP
Species Human
Gene Type protein-coding
Description calpain 2, (m/II) large subunit
Other Description CANP 2|M-calpain|calcium-activated neutral proteinase 2|calpain 2, large [catalytic] subunit|calpain 2, large subunit|calpain M-type|calpain large polypeptide L2|calpain, large polypeptide L2|calpain-2 catalytic subunit|calpain-2 large subunit|millimolar-calpain
Swissprots Q8WU26 A6NDG7 Q16738 E7ES58 Q9HBB1 B7ZA96 P17655 Q6PJT3
Accessions AAA52760 AAV80421 EAW93249 EAW93250 EAW93251 P17655 AB209855 BAD93092 AF261089 AAF99682 AI089162 AK023851 AK055046 AK056838 AK097247 BAG53441 AK124751 BAC85936 AK297800 BAG60139 AK303952 BAG64879 AK315179 BAG37620 AK316211 BAH14582 BC007686 AAH07686 BC011828 AAH11828 BC021303 AAH21303 DA448245 DQ893312 ABM84238 DQ893620 ABM84546 EU176804 ABW03605 M23254 AAA35645 XM_011544286 XP_011542588 NM_001146068 NP_001139540 NM_001748 NP_001739
Function Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). {ECO:0000269|PubMed:17650508}.
Subcellular Location Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Tissue Specificity Ubiquitous.
Top Pathways Apoptosis, Focal adhesion, Alzheimer's disease, Protein processing in endoplasmic reticulum

Calpain 2 CRISPR/Cas9 KO Plasmid (h) - sc-401113 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 HDR Plasmid (h) - sc-401113-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 Double Nickase Plasmid (h) - sc-401113-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 Double Nickase Plasmid (h2) - sc-401113-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 CRISPR Activation Plasmid (h) - sc-401113-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 CRISPR Activation Plasmid (h2) - sc-401113-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 Lentiviral Activation Particles (h) - sc-401113-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 Lentiviral Activation Particles (h2) - sc-401113-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Calpain 2 siRNA (h) - sc-41459 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calpain 2 shRNA Plasmid (h) - sc-41459-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calpain 2 shRNA (h) Lentiviral Particles - sc-41459-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calpain 2 RNAi - H00000824-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU025391 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU104061 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5344 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5344 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CAPN2 siRNA (Human) - CRH0578 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CAPN2 - MBS8229957 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CAPN2 (NM_001748.4) - SHH254333 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CAPN2(NM_001748.4) - SHG140487 from Creative biogene

Category siRNA
Species Reactivities Human

Human CAPN2 siRNA - orb261080 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CAPN2 shRNA Plasmid (Human) - CHH0578 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CAPN2 miRNA 3'UTR clone - MiUTR1H-01651 from Creative biogene

Species Reactivities Human

CAPN2 miRNA 3'UTR clone - MiUTR3H-00329 from Creative biogene

Species Reactivities Human
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