| Gene Symbol |
USPL1
|
| Entrez Gene |
10208
|
| Alt Symbol |
C13orf22, D13S106E, bA121O19.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin specific peptidase like 1
|
| Other Description |
SUMO-specific isopeptidase USPL1|highly charged protein|ubiquitin-specific peptidase-like protein 1
|
| Swissprots |
Q8IYE8 Q8IY30 Q5W0Q7 Q6AI45 Q14109
|
| Accessions |
CCQ43337 EAX08466 Q5W0Q7 AK057514 BAG51926 AK289826 BAF82515 AL832776 BC012594 BC036027 AAH36027 BC038103 AAH38103 BI752017 CR627370 CAH10469 X59131 CAA41848 XM_005266213 XP_005266270 XM_005266214 XP_005266271 XM_006719751 XP_006719814 XM_011534862 XP_011533164 NM_005800 NP_005791
|
| Function |
SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms. May have non-catalytic functions in Cajal bodies organization and cell proliferation. {ECO:0000269|PubMed:22878415}.
|
| Subcellular Location |
Nucleus, Cajal body {ECO:0000269|PubMed:22878415}.
|