| Gene Symbol |
SLC39A14
|
| Entrez Gene |
23516
|
| Alt Symbol |
LZT-Hs4, NET34, ZIP14, cig19
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 39 (zinc transporter), member 14
|
| Other Description |
LIV-1 subfamily of ZIP zinc transporter 4|ZIP-14|Zrt-, Irt-like protein 14|solute carrier family 39 (metal ion transporter), member 14|solute carrier family 39 member 14|zinc transporter ZIP14|zrt- and Irt-like protein 14
|
| Swissprots |
A6NH98 Q15043 D3DSR4 B4DIW3 Q96BB3 Q6ZME8 B6EU88
|
| Accessions |
EAW63680 EAW63681 EAW63682 EAW63683 Q15043 AA181885 AF026940 AK172810 BAD18780 AK295807 BAG58625 BC000068 BC015770 AAH15770 BX648538 D31887 BAA06685 DC323208 DC423882 JF432188 ADZ15405 XM_005273463 XP_005273520 XM_005273465 XP_005273522 XM_005273466 XP_005273523 XM_006716323 XP_006716386 XM_006716324 XP_006716387 XM_011544477 XP_011542779 XM_011544478 XP_011542780 NM_001128431 NP_001121903 NM_001135153 NP_001128625 NM_001135154 NP_001128626 NM_015359 NP_056174
|
| Function |
May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake. {ECO:0000250, ECO:0000269|PubMed:15642354}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, lamellipodium {ECO:0000269|PubMed:12659941, ECO:0000269|PubMed:15642354}. Note=Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.
|
| Tissue Specificity |
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes. {ECO:0000269|PubMed:15642354, ECO:0000269|PubMed:7584044}.
|
