| Gene Symbol |
RFX5
|
| Entrez Gene |
5993
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulatory factor X, 5 (influences HLA class II expression)
|
| Other Description |
DNA-binding protein RFX5|regulatory factor X 5
|
| Swissprots |
Q5VWC3 E9PFU4 D3DV19 P48382 B7Z848
|
| Accessions |
CDL97008 CDL97009 EAW53446 EAW53447 EAW53448 P48382 AK223526 BAD97246 AK302891 BAH13834 AK309072 AK311525 AK312289 BAG35216 AL050135 CAB43285 BC017471 AAH17471 BX423384 DQ892382 ABM83308 DQ895594 ABM86520 X85786 CAA59771 XM_005245405 XP_005245462 XM_005245406 XP_005245463 XM_011509847 XP_011508149 XM_011509848 XP_011508150 XM_011509849 XP_011508151 XM_011509850 XP_011508152 NM_000449 NP_000440 NM_001025603 NP_001020774
|
| Function |
Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Primary immunodeficiency, Tuberculosis, Antigen processing and presentation
|