Gene Symbol | RFX5 |
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Entrez Gene | 5993 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | regulatory factor X, 5 (influences HLA class II expression) |
Other Description | DNA-binding protein RFX5|regulatory factor X 5 |
Swissprots | Q5VWC3 E9PFU4 D3DV19 P48382 B7Z848 |
Accessions | CDL97008 CDL97009 EAW53446 EAW53447 EAW53448 P48382 AK223526 BAD97246 AK302891 BAH13834 AK309072 AK311525 AK312289 BAG35216 AL050135 CAB43285 BC017471 AAH17471 BX423384 DQ892382 ABM83308 DQ895594 ABM86520 X85786 CAA59771 XM_005245405 XP_005245462 XM_005245406 XP_005245463 XM_011509847 XP_011508149 XM_011509848 XP_011508150 XM_011509849 XP_011508151 XM_011509850 XP_011508152 NM_000449 NP_000440 NM_001025603 NP_001020774 |
Function | Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Primary immunodeficiency, Tuberculosis, Antigen processing and presentation |
RFX5 CRISPR/Cas9 KO Plasmid (h) - sc-408146 from Santa Cruz Biotechnology
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RFX5 HDR Plasmid (h) - sc-408146-HDR from Santa Cruz Biotechnology
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RFX5 Double Nickase Plasmid (h) - sc-408146-NIC from Santa Cruz Biotechnology
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RFX5 Double Nickase Plasmid (h2) - sc-408146-NIC-2 from Santa Cruz Biotechnology
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RFX5 CRISPR Activation Plasmid (h) - sc-408146-ACT from Santa Cruz Biotechnology
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RFX5 CRISPR Activation Plasmid (h2) - sc-408146-ACT-2 from Santa Cruz Biotechnology
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RFX5 Lentiviral Activation Particles (h) - sc-408146-LAC from Santa Cruz Biotechnology
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RFX5 Lentiviral Activation Particles (h2) - sc-408146-LAC-2 from Santa Cruz Biotechnology
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RFX5 siRNA (h) - sc-37747 from Santa Cruz Biotechnology
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RFX5 shRNA Plasmid (h) - sc-37747-SH from Santa Cruz Biotechnology
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RFX5 shRNA (h) Lentiviral Particles - sc-37747-V from Santa Cruz Biotechnology
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RFX5 RNAi - H00005993-R02 from Novus Biologicals
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MISSION® esiRNA - EHU031121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18188 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18188 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09728 from Sigma-Aldrich
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RFX5 siRNA (Human) - CRH4061 from Cohesion Biosciences
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RFX5 RNAi - H00005993-R01 from Novus Biologicals
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RFX5 - MBS8211616 from MyBioSource
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shRNA set against Human RFX5 (NM_000449.3) - SHH392436 from Creative biogene
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shRNA set against Human RFX5(NM_000449.3) - SHR169752 from Creative biogene
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RFX5 shRNA Plasmid (Human) - CHH4061 from Cohesion Biosciences
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RFX5 miRNA 3'UTR clone - MiUTR1H-08764 from Creative biogene
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RFX5 miRNA 3'UTR clone - MiUTR3H-04463 from Creative biogene
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