| Gene Symbol |
KANSL1
|
| Entrez Gene |
284058
|
| Alt Symbol |
CENP-36, KDVS, KIAA1267, MSL1v1, NSL1, hMSL1v1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
KAT8 regulatory NSL complex subunit 1
|
| Other Description |
MLL1/MLL complex subunit KANSL1|MSL1 homolog 1|NSL complex protein NSL1|centromere protein 36|male-specific lethal 1 homolog|non-specific lethal 1 homolog
|
| Swissprots |
Q6AW85 Q9BRH0 Q7Z3B3 Q9NTE7 Q9ULF3 Q8IYH1 A8K5E4 Q9UFT0
|
| Accessions |
CAD34785 EAW93576 EAW93577 Q7Z3B3 AB033093 BAA86581 AI253068 AK094946 BAG52961 AK291259 BAF83948 AK310569 AL117476 CAB55949 AL137317 CAB70694 AM392814 CAL37692 AM393686 CAL38562 BC035892 AAH35892 BC098376 AAH98376 BX538006 CAD97958 BX648760 CAH10565 DA010621 XM_005257232 XP_005257289 XM_005257233 XP_005257290 XM_005275644 XP_005275701 XM_005275645 XP_005275702 XM_006721823 XP_006721886 XM_006721824 XP_006721887 XM_011524628 XP_011522930 XM_011524629 XP_011522931 XM_011524630 XP_011522932 XM_011524631 XP_011522933 XM_011524632 XP_011522934 XM_011546340 XP_011544642 XM_011546341 XP_011544643 XM_011546342 XP_011544644 XM_011546343 XP_011544645 XM_011546344 XP_011544646 XM_011547471 XP_011545773 XM_011547472 XP_011545774 XM_011547473 XP_011545775 XM_011547474 XP_011545776 XM_011547475 XP_011545777 NM_001193465 NP_001180394 NM_001193466 NP_001180395 NM_015443 NP_056258
|
| Function |
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. {ECO:0000269|PubMed:20018852, ECO:0000269|PubMed:22547026}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:20018852}. Nucleus. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}.
|
| Tissue Specificity |
Expressed in the brain. {ECO:0000269|PubMed:11641718}.
|