Gene Symbol | ARL2BP |
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Entrez Gene | 23568 |
Alt Symbol | BART, BART1, RP66 |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribosylation factor-like 2 binding protein |
Other Description | ADP-ribosylation factor-like protein 2-binding protein|ARF-like 2-binding protein|ARL2-binding protein|Arf-like 2 binding protein BART1|binder of ARF2 protein 1|binder of Arl Two|binder of Arl2|retinitis pigmentosa 66 (autosomal recessive) |
Swissprots | B3KQJ5 Q504R0 Q9Y2Y0 |
Accessions | CAD88076 CAF86252 EAW82913 EAW82914 Q9Y2Y0 AF126062 AAD20633 AK075050 BAG52057 AK298758 BAG60900 AK311018 BC003087 AAH03087 BC094878 AAH94878 BF590083 XM_011522977 XP_011521279 NM_012106 NP_036238 |
Function | Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. {ECO:0000269|PubMed:18234692}. |
Subcellular Location | Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Note=The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. In retina photoreceptor cells, localized in the distal connecting cilia, basal body, ciliary-associated centriole, and ciliary rootlet. Interaction with ARL2 may be required for cilia basal body localization. {ECO:0000250}. |
Tissue Specificity | Expressed in retina pigment epithelial cells (at protein level). Widely expressed. {ECO:0000269|PubMed:10488091, ECO:0000269|PubMed:23849777}. |
Human ARL2BP full length protein - ab101067 from Abcam
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ARL2BP / BART Antibody Blocking Peptide - LS-E22724 from LifeSpan Bioscience
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ARL2BP Recombinant Protein - H00023568-P01 from Novus Biologicals
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Recombinant Human ARL2BP Protein - NBP1-50851 from Novus Biologicals
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ARL2BP Protein (OPPA02567) - OPPA02567 from Aviva Systems Biology
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Human ARL2BP protein - orb245197 from Biorbyt
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Human ARL2BP protein (His Tag) - orb138205 from Biorbyt
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Human ARL2BP protein - orb167917 from Biorbyt
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ARL2BP protein (His tag) - 80R-1526 from Fitzgerald
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ARL2BP (1-163, His-tag) - AR09704PU-L from Acris Antibodies
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ARL2BP (1-163, His-tag) - AR09704PU-N from Acris Antibodies
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ARL2BP - H00023568-P01-02 from Acris Antibodies
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ARL2BP, 1-163aa, Human, His tag, E.coli - 01-1904-2BP from ARP American Research Products
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ARL2BP fusion protein - Ag0138 from Proteintech Group
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ARL2BP Human - PRPS-281 from NeoScientific
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Recombinant Human ADP-Ribosylation Factor-Like 2 Binding Protein - BP001811-PRO-274 from Syd Labs
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ARL2BP, 1-163aa, Recombinant Protein - GWB-P1273L from Genway Biotech
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ARL2BP Human Protein - GWB-BSP386 from Genway Biotech
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Recombinant Human ARL2BP, His-tagged - ARL2BP-27186TH from Creative Biomart
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Recombinant Human ARL2BP, His-tagged - ARL2BP-2878H from Creative Biomart
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Recombinant Human ADP-Ribosylation Factor-Like 2 Binding Protein, His-tagged - ARL2BP-6904H from Creative Biomart
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Recombinant Human ARL2BP, GST-tagged - ARL2BP-9855H from Creative Biomart
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Recombinant Human ARL2BP, His tagged - ARL2BP-453H from Creative Biomart
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ARL2BP 1-163aa - CMB-598 from Reagent Proteins
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ARL2BP - NKX-319 from Reagent Proteins
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