TECR

Gene Symbol	TECR
Entrez Gene	9524
Alt Symbol	GPSN2, MRT14, SC2, TER
Species	Human
Gene Type	protein-coding
Description	trans-2,3-enoyl-CoA reductase
Other Description	glycoprotein, synaptic 2|synaptic glycoprotein SC2|very-long-chain enoyl-CoA reductase
Swissprots	Q6IBB2 Q9BWK3 O75350 Q9NZ01 Q9Y6P0 B2RD55
Accessions	EAW84434 EAW84435 Q9NZ01 AF038958 AAC39872 AF038959 AAC39873 AF222742 AAF32373 AK001416 BAG50909 AK094087 BAG52813 AK299134 BAG61186 AK315412 BAG37802 BC000174 AAH00174 BC002425 AAH02425 BC005384 BC005952 AAH05952 BC007801 AAH07801 BC013881 AAH13881 BC034484 BG705196 BT007179 AAP35843 CR456892 CAG33173 DB491783 DQ891949 ABM82875 DQ895135 ABM86061 EU832830 ACE87841 GQ129437 ACT64571 XM_006722945 XP_006723008 XM_006722947 XP_006723010 XM_011528442 XP_011526744 NM_138501 NP_612510 NR_038103 NR_038104 NM_004868
Function	Catalyzes the last of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:12482854}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12482854}; Multi-pass membrane protein {ECO:0000269|PubMed:12482854}.
Tissue Specificity	Expressed in most tissues tested. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:12482854}.
Top Pathways	Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GPSN2 full length protein - ab160529 from Abcam Category Protein Source Wheat germ Species Human

TECR / TER Antibody Blocking Peptide - LS-E17519 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TECR / TER Antibody Blocking Peptide - LS-E17520 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TECR / TER Antibody Blocking Peptide - LS-E10318 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Synaptic glycoprotein SC2 Protein - H00009524-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GPSN2-Antibody-C-term-Blocking-Peptide - BP9788b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPSN2 Blocking Peptide - 33R-7077 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPSN2 Blocking Peptide - 33R-5372 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TECR / GPSN2 - H00009524-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

GPSN2 fusion protein - ag6986 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GPSN2 fusion protein - ag7241 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Synaptic glycoprotein SC2 Protein - NBP1-92465PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TECR Blocking Peptide - abx061838 from Abbexa Category Peptide

Synaptic glycoprotein SC2 Recombinant Protein Antigen - NBP2-49230PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

TECR Peptide, Human - M34GP15775H from Creative Peptides Category Peptide Source Synthetic. Species Human

TECR Blocking Peptide - CBP7228 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

Search more