TECR

Gene Symbol	TECR
Entrez Gene	9524
Alt Symbol	GPSN2, MRT14, SC2, TER
Species	Human
Gene Type	protein-coding
Description	trans-2,3-enoyl-CoA reductase
Other Description	glycoprotein, synaptic 2|synaptic glycoprotein SC2|very-long-chain enoyl-CoA reductase
Swissprots	Q6IBB2 Q9BWK3 O75350 Q9NZ01 Q9Y6P0 B2RD55
Accessions	EAW84434 EAW84435 Q9NZ01 AF038958 AAC39872 AF038959 AAC39873 AF222742 AAF32373 AK001416 BAG50909 AK094087 BAG52813 AK299134 BAG61186 AK315412 BAG37802 BC000174 AAH00174 BC002425 AAH02425 BC005384 BC005952 AAH05952 BC007801 AAH07801 BC013881 AAH13881 BC034484 BG705196 BT007179 AAP35843 CR456892 CAG33173 DB491783 DQ891949 ABM82875 DQ895135 ABM86061 EU832830 ACE87841 GQ129437 ACT64571 XM_006722945 XP_006723008 XM_006722947 XP_006723010 XM_011528442 XP_011526744 NM_138501 NP_612510 NR_038103 NR_038104 NM_004868
Function	Catalyzes the last of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:12482854}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12482854}; Multi-pass membrane protein {ECO:0000269|PubMed:12482854}.
Tissue Specificity	Expressed in most tissues tested. Highly expressed in skeletal muscle. {ECO:0000269|PubMed:12482854}.
Top Pathways	Fatty acid elongation, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GPSN2 (L-12) - sc-168030 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-GPSN2 antibody - ab103454 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-GPSN2 antibody - ab75786 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295, APC) - LS-C258010 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295, Biotin) - LS-C258011 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295, Azide-free, HRP) - LS-C258012 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295, FITC) - LS-C258013 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295, PE) - LS-C258014 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa259-308) - LS-C199013 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa274-304) - LS-C321771 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa110-159) - LS-C81236 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa218-267) - LS-C81237 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295) - LS-C166651 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TECR / TER Antibody (aa268-295, AP) - LS-C258009 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Synaptic glycoprotein SC2 Antibody - NBP1-60088 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

Synaptic glycoprotein SC2 Antibody - NBP1-92465 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-GPSN2(C-TERMINAL) antibody produced in rabbit - SAB1307138 from Sigma-Aldrich Prices $326.00 Sizes 40 tst Host Rabbit Clonality Polyclonal

Anti-GPSN2 antibody produced in rabbit - SAB2100966 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TECR antibody produced in rabbit - HPA029780 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-GPSN2 antibody produced in rabbit - AV48431 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

GPSN2 antibody - middle region (ARP48431_P050) - ARP48431_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GPSN2 antibody - C-terminal region (ARP48432_P050) - ARP48432_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GPSN2-Antibody-C-term - AP9788b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

TECR Antibody - C-terminal region (OAAB06389) - OAAB06389 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

GPSN2 antibody - GTX87026 from GeneTex Prices $319.00 Sizes 100 μg Host Rabbit Clonality Polyclonal

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