Gene Symbol |
SPTAN1
|
Entrez Gene |
6709
|
Alt Symbol |
EIEE5, NEAS, SPTA2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
spectrin, alpha, non-erythrocytic 1
|
Other Description |
alpha-II spectrin|alpha-fodrin|fodrin alpha chain|spectrin alpha chain, non-erythrocytic 1|spectrin, non-erythroid alpha chain|spectrin, non-erythroid alpha subunit
|
Swissprots |
Q15324 Q9P0V0 Q5VXV5 Q7Z6M5 Q13813 Q16606 Q59EF1 Q5VXV6 Q13186
|
Accessions |
AAF26672 EAW87805 EAW87806 EAW87807 EAW87808 EAW87809 EAW87810 EAW87811 EAW87812 EAW87813 Q13813 AB191262 BAD52438 AB209860 BAD93097 AK026484 AK126576 AK294753 BAG57892 AK300386 BAG62120 AK307676 AK309836 AK310696 AL110273 CAB53710 BC034956 BC051801 BC053521 AAH53521 BP200529 DC359079 J05243 AAA51790 M18627 AAA51702 M19725 AAA59904 M24773 AAA52468 U26396 AAB60364 U83867 AAB41498 X86901 CAA60503 XM_006717245 XP_006717308 XM_006717246 XP_006717309 XM_006717247 XP_006717310 XM_006717248 XP_006717311 XM_006717249 XP_006717312 XM_006717250 XP_006717313 XM_006717251 XP_006717314 XM_006717252 XP_006717315 XM_006717253 XP_006717316 XM_006717254 XP_006717317 NM_001130438 NP_001123910 NM_001195532 NP_001182461 NM_003127 NP_003118
|
Function |
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
|
Subcellular Location |
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. {ECO:0000250}.
|
Top Pathways |
Tight junction
|