| Gene Symbol |
WFIKKN2
|
| Entrez Gene |
124857
|
| Alt Symbol |
GASP-1, WFDC20B, WFIKKNRP, hGASP-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
|
| Other Description |
WAP four-disulfide core domain 20B|WAP, FS, Ig, two KU and NTR module related protein|WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2|WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein|WFIKKN-related protein|growth and differentiation factor-associated serum protein 1|multivalent protease inhibitor protein
|
| Swissprots |
Q6UXZ9 Q8TEU8
|
| Accessions |
EAW94579 EAW94580 Q8TEU8 AF468657 AAL77058 AK127743 BAG54563 AK131196 BAD18391 AK298172 BAH12737 AK312821 BAG35678 AL537450 AY358142 AAQ88509 BC140842 AAI40843 BC140844 AAI40845 BG221308 BQ954191 DB235333 NM_175575 NP_783165
|
| Function |
Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted {ECO:0000250}.
|
| Tissue Specificity |
Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney. {ECO:0000269|PubMed:11928817}.
|
![Western Blot: WFIKKN2 Overexpression Lysate (Adult Normal) [NBP2-05066] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for WFIKKN2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5059_WFIKKN2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05066-img0001.jpg)