Gene Symbol | WFIKKN2 |
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Entrez Gene | 124857 |
Alt Symbol | GASP-1, WFDC20B, WFIKKNRP, hGASP-1 |
Species | Human |
Gene Type | protein-coding |
Description | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 |
Other Description | WAP four-disulfide core domain 20B|WAP, FS, Ig, two KU and NTR module related protein|WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2|WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein|WFIKKN-related protein|growth and differentiation factor-associated serum protein 1|multivalent protease inhibitor protein |
Swissprots | Q6UXZ9 Q8TEU8 |
Accessions | EAW94579 EAW94580 Q8TEU8 AF468657 AAL77058 AK127743 BAG54563 AK131196 BAD18391 AK298172 BAH12737 AK312821 BAG35678 AL537450 AY358142 AAQ88509 BC140842 AAI40843 BC140844 AAI40845 BG221308 BQ954191 DB235333 NM_175575 NP_783165 |
Function | Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney. {ECO:0000269|PubMed:11928817}. |
WFIKKN2 CRISPR/Cas9 KO Plasmid (h) - sc-409024 from Santa Cruz Biotechnology
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WFIKKN2 HDR Plasmid (h) - sc-409024-HDR from Santa Cruz Biotechnology
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WFIKKN2 Double Nickase Plasmid (h) - sc-409024-NIC from Santa Cruz Biotechnology
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WFIKKN2 Double Nickase Plasmid (h2) - sc-409024-NIC-2 from Santa Cruz Biotechnology
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WFIKKN2 CRISPR Activation Plasmid (h) - sc-409024-ACT from Santa Cruz Biotechnology
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WFIKKN2 CRISPR Activation Plasmid (h2) - sc-409024-ACT-2 from Santa Cruz Biotechnology
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WFIKKN2 Lentiviral Activation Particles (h) - sc-409024-LAC from Santa Cruz Biotechnology
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WFIKKN2 Lentiviral Activation Particles (h2) - sc-409024-LAC-2 from Santa Cruz Biotechnology
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WFIKKN2 siRNA (h) - sc-93807 from Santa Cruz Biotechnology
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WFIKKN2 shRNA Plasmid (h) - sc-93807-SH from Santa Cruz Biotechnology
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WFIKKN2 shRNA (h) Lentiviral Particles - sc-93807-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU150681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22890 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22890 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08920 from Sigma-Aldrich
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WFIKKN2 siRNA (Human) - CRJ4788 from Cohesion Biosciences
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WFIKKN2 - MBS8223658 from MyBioSource
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shRNA set against Human WFIKKN2 (NM_175575.5) - SHH446932 from Creative biogene
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Human WFIKKN2 siRNA - orb275289 from Biorbyt
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WFIKKN2 shRNA Plasmid (Human) - CHJ4788 from Cohesion Biosciences
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WFIKKN2 miRNA 3'UTR clone - MiUTR4H-TG09881 from Creative biogene
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