Gene Symbol | SPCS3 |
---|---|
Entrez Gene | 60559 |
Alt Symbol | PRO3567, SPC22/23, SPC3, YLR066W |
Species | Human |
Gene Type | protein-coding |
Description | signal peptidase complex subunit 3 homolog (S. cerevisiae) |
Other Description | SPase 22 kDa subunit|SPase 22/23 kDa subunit|microsomal signal peptidase 22/23 kDa subunit|microsomal signal peptidase 23 kDa subunit|signal peptidase complex subunit 3 |
Swissprots | P61009 |
Accessions | CAH05566 EAX04718 EAX04719 P61009 AK026302 BAB15437 AK092634 AL136660 CAB66595 AY359044 AAQ89403 BC043490 BC047290 AAH47290 BC053883 DB285025 EU831652 ACE87252 EU831735 ACE86569 HQ448610 ADQ33088 NM_021928 NP_068747 |
Function | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}. |
Subcellular Location | Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Protein export |