Gene Symbol | C1GALT1C1 |
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Entrez Gene | 29071 |
Alt Symbol | C1GALT2, C38H2-L1, COSMC, HSPC067, MST143, TNPS |
Species | Human |
Gene Type | protein-coding |
Description | C1GALT1-specific chaperone 1 |
Other Description | C1Gal-T2|C38H2-like protein 1|beta 1,3-galactosyltransferase 2|core 1 beta1,3-galactosyltransferase 2|core 1 beta3-Gal-T2|core 1 beta3-galactosyltransferase-specific molecular chaperone |
Swissprots | A8K246 Q96EU7 Q9NZX1 Q8WWS3 |
Accessions | EAX11873 Q96EU7 AA578739 AB084170 BAC41493 AF088029 AF161552 AAF29039 AF177284 AAQ13670 AJ238398 CAC80277 AK290111 BAF82800 AY159319 AAN78129 AY358642 AAQ89005 BC011930 AAH11930 BC012502 BC050441 AAH50441 BG779539 BM971206 JF432849 ADZ16066 NM_001011551 NP_001011551 NM_152692 NP_689905 |
Function | Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1). {ECO:0000269|PubMed:12464682}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus. {ECO:0000269|PubMed:12361956}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Cosmc (H-10) - sc-271829 from Santa Cruz Biotechnology
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Cosmc (P-14) - sc-67482 from Santa Cruz Biotechnology
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Cosmc (H-270) - sc-68410 from Santa Cruz Biotechnology
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Anti-C1GALT1C1 antibody - ab68310 from Abcam
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Anti-C1GALT1C1 antibody - N-terminal - ab93483 from Abcam
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Anti-C1GALT1C1 antibody - N-terminal - ab140292 from Abcam
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Anti-C1GALT1C1 Antibody - LS-C306621 from LifeSpan Bioscience
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C1GALT1C1 Antibody - NBP1-88478 from Novus Biologicals
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C1GALT1C1 Antibody - H00029071-B01P from Novus Biologicals
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Anti-C1GALT1C1 antibody produced in rabbit - HPA015632 from Sigma-Aldrich
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Anti-C1GALT1C1 antibody produced in mouse - SAB1407373 from Sigma-Aldrich
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C1GALT1C1 antibody [N3C3] - GTX115877 from GeneTex
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C1GALT1C1 antibody - 70R-16072 from Fitzgerald
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C1GALT1C1 antibody - 19254-1-AP from Acris Antibodies
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C1GALT1C1 antibody - H00029071-B01P from Acris Antibodies
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COSMC antibody - 19254-1-AP from Proteintech Group
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COSMC antibody - 14290-1-AP from Proteintech Group
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Anti-C1GALT1C1 antibody - STJ29727 from St John's Laboratory Ltd
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C1GALT1-specific chaperone 1 , Polyclonal Antibody - MBS712710 from MyBioSource
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C1GALT1C1, Polyclonal Antibody - MBS2526472 from MyBioSource
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C1GALT1C1, Polyclonal Antibody - MBS2522386 from MyBioSource
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C1GALT1C1, Polyclonal Antibody - MBS6008211 from MyBioSource
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C1GALT1C1 Antibody - EPP10991 from Elabscience
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C1GALT1C1 Antibody - EPP10992 from Elabscience
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Anti-C1GALT1C1 monoclonal antibody - DCABH-14775 from Creative Diagnostics
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