| Gene Symbol |
TTLL7
|
| Entrez Gene |
79739
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tubulin tyrosine ligase-like family member 7
|
| Other Description |
testis development protein NYD-SP30|tubulin polyglutamylase TTLL7|tubulin tyrosine ligase-like family, member 7|tubulin--tyrosine ligase-like protein 7
|
| Swissprots |
Q6ZT98 Q5TAX8 Q9H5U4 Q86YS1 Q6P990 Q5TAX9
|
| Accessions |
EAW73251 EAW73252 Q6ZT98 AK026686 BAB15526 AK094174 AK126792 BAC86695 AK128604 BAC87524 AK225574 AY170843 AAO37763 BC028350 AAH28350 BC032829 BC048970 AAH48970 BC060878 AAH60878 BG718305 JF432361 ADZ15578 XM_005271208 XP_005271265 XM_005271211 XP_005271268 XM_011542155 XP_011540457 XM_011542156 XP_011540458 XM_011542157 XP_011540459 XM_011542158 XP_011540460 XM_011542159 XP_011540461 XR_946758 XR_946759 XR_946760 NM_024686 NP_078962
|
| Function |
Polyglutamylase which preferentially modifies beta- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Perikaryon {ECO:0000250}. Note=In cells with primary cilia, found in both cilia and basal bodies. In neuronal cells, found in dendrites and perikaryon (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus and cerebellum. {ECO:0000269|PubMed:16901895}.
|