| Gene Symbol |
POLR2K
|
| Entrez Gene |
5440
|
| Alt Symbol |
ABC10-alpha, RPABC4, RPB10alpha, RPB12, RPB7.0, hRPB7.0, hsRPB10a
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
| Other Description |
DNA directed RNA polymerases I, II, and III 7.0 kda polypeptide|DNA-directed RNA polymerase II subunit K|DNA-directed RNA polymerases I, II, and III subunit RPABC4|RNA polymerase II 7.0 kDa subunit|RNA polymerases I, II, and III subunit ABC4
|
| Swissprots |
Q6IBD4 P53803
|
| Accessions |
CAB91873 EAW91798 EAW91799 P53803 BC000806 AAH00806 BC018157 AAH18157 CR456870 CAG33151 DQ891159 ABM82085 DQ894340 ABM85266 Z47727 CAA87656 NM_005034 NP_005025
|
| Function |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Top Pathways |
Huntington's disease, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase
|
![Western Blot: POLR2K Overexpression Lysate (Adult Normal) [NBL1-14587] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for POLR2K.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11715_POLR2K%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-14587-img0002.jpg)