| Gene Symbol |
RGS9BP
|
| Entrez Gene |
388531
|
| Alt Symbol |
PERRS, R9AP, RGS9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulator of G protein signaling 9 binding protein
|
| Other Description |
RGS9 anchor protein|RGS9-anchoring protein|regulator of G-protein signaling 9-binding protein
|
| Swissprots |
Q6ZS82 Q6ZVJ6
|
| Accessions |
Q6ZS82 AF086461 AK124499 BAC85865 AK127646 BAC87072 BC172343 AAI72343 NM_207391 NP_997274
|
| Function |
Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
|