Gene Symbol | RGS9BP |
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Entrez Gene | 388531 |
Alt Symbol | PERRS, R9AP, RGS9 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G protein signaling 9 binding protein |
Other Description | RGS9 anchor protein|RGS9-anchoring protein|regulator of G-protein signaling 9-binding protein |
Swissprots | Q6ZS82 Q6ZVJ6 |
Accessions | Q6ZS82 AF086461 AK124499 BAC85865 AK127646 BAC87072 BC172343 AAI72343 NM_207391 NP_997274 |
Function | Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. |
R9AP CRISPR/Cas9 KO Plasmid (h) - sc-415784 from Santa Cruz Biotechnology
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R9AP HDR Plasmid (h) - sc-415784-HDR from Santa Cruz Biotechnology
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R9AP Double Nickase Plasmid (h) - sc-415784-NIC from Santa Cruz Biotechnology
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R9AP Double Nickase Plasmid (h2) - sc-415784-NIC-2 from Santa Cruz Biotechnology
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R9AP CRISPR Activation Plasmid (h) - sc-415784-ACT from Santa Cruz Biotechnology
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R9AP CRISPR Activation Plasmid (h2) - sc-415784-ACT-2 from Santa Cruz Biotechnology
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R9AP Lentiviral Activation Particles (h) - sc-415784-LAC from Santa Cruz Biotechnology
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R9AP Lentiviral Activation Particles (h2) - sc-415784-LAC-2 from Santa Cruz Biotechnology
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R9AP siRNA (h) - sc-97282 from Santa Cruz Biotechnology
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R9AP shRNA Plasmid (h) - sc-97282-SH from Santa Cruz Biotechnology
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R9AP shRNA (h) Lentiviral Particles - sc-97282-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN18236 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18236 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09742 from Sigma-Aldrich
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RGS9BP siRNA (Human) - CRJ7803 from Cohesion Biosciences
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RGS9BP - MBS8209474 from MyBioSource
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shRNA set against Human RGS9BP (NM_207391.2) - SHH395060 from Creative biogene
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RGS9BP shRNA Plasmid (Human) - CHJ7803 from Cohesion Biosciences
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RGS9BP miRNA 3'UTR clone - MiUTR1H-08797 from Creative biogene
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