KCNJ1

Gene Symbol	KCNJ1
Entrez Gene	3758
Alt Symbol	KIR1.1, ROMK, ROMK1
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 1
Other Description	ATP-regulated potassium channel ROM-K|ATP-sensitive inward rectifier potassium channel 1|inward rectifier K(+) channel Kir1.1|inwardly rectifying K+ channel|potassium channel, inwardly rectifying subfamily J member 1|potassium inwardly-rectifying channel, subfamily J, member 1
Swissprots	P48048 B2RMR4 Q6LD67
Accessions	AAC51220 AAC51221 AAC51222 EAW67721 EAW67722 EAW67723 EAW67724 EAW67725 P48048 AI795925 AK290797 BAF83486 AK308032 AK308033 AK314267 AW611934 BC063109 BC074752 AAH74752 BC136360 AAI36361 BC136361 AAI36362 BE466312 DA622270 DA629130 DB199073 S78737 AAB35012 U03884 AAA20594 U12541 AAA61712 U12542 AAA61713 U12543 AAA61714 U12544 AAA61715 U12545 AAA61716 NM_000220 NP_000211 NM_153764 NP_722448 NM_153765 NP_722449 NM_153766 NP_722450 NM_153767 NP_722451
Function	In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12684516}; Multi-pass membrane protein {ECO:0000269|PubMed:12684516}. Note=Phosphorylation at Ser-44 by SGK1 is necessary for its expression at the cell membrane.
Tissue Specificity	In the kidney and pancreatic islets. Lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver. {ECO:0000269|PubMed:7635463}.
Top Pathways	Aldosterone-regulated sodium reabsorption, Gastric acid secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), Human, ELISA Kit - E01A1890 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

ATP sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7208516 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7208961 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7219978 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7238483 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7241818 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7248225 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7224172 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7212438 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7240863 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7208883 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7251158 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1 (KCNJ1), ELISA Kit - MBS7205859 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1, KCNJ1/ROM-K, ELISA Kit - MBS9307178 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1, KCNJ1/ROM-K, ELISA Kit - MBS9305741 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 1, KCNJ1/ROM-K, ELISA Kit - MBS9307073 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

potassium inwardly-rectifying channel, subfamily J, member 1, ELISA Kit - MBS9335530 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human KCNJ1 ELISA Kit - E004043 from Biobool Category ELISA Kit

Human KCNJ1/ROM-K ELISA Kit - E004122 from Biobool Category ELISA Kit

anti-KCNJ1 / ROMK antibody - ARG64817 from Arigo Biolaboratories Category ELISA Kit

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