Gene Symbol |
TAS1R3
|
Entrez Gene |
83756
|
Alt Symbol |
T1R3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
taste receptor, type 1, member 3
|
Other Description |
sweet taste receptor T1R3|taste receptor type 1 member 3
|
Swissprots |
Q8NGW9 Q5TA49 Q7RTX0
|
Accessions |
BAC05873 CAL69810 CAS03328 CAS03502 CAV33588 CBJ18622 EAW56228 Q7RTX0 AK122959 BC152912 AAI52913 BK000152 DAA00013 XM_011542239 XP_011540541 NM_152228 NP_689414
|
Function |
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. {ECO:0000250, ECO:0000269|PubMed:11917125, ECO:0000269|PubMed:12892531}.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Taste transduction, Carbohydrate digestion and absorption
|