Gene Symbol | TAS1R3 |
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Entrez Gene | 83756 |
Alt Symbol | T1R3 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 1, member 3 |
Other Description | sweet taste receptor T1R3|taste receptor type 1 member 3 |
Swissprots | Q8NGW9 Q5TA49 Q7RTX0 |
Accessions | BAC05873 CAL69810 CAS03328 CAS03502 CAV33588 CBJ18622 EAW56228 Q7RTX0 AK122959 BC152912 AAI52913 BK000152 DAA00013 XM_011542239 XP_011540541 NM_152228 NP_689414 |
Function | Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. {ECO:0000250, ECO:0000269|PubMed:11917125, ECO:0000269|PubMed:12892531}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Taste transduction, Carbohydrate digestion and absorption |
T1R3 CRISPR/Cas9 KO Plasmid (h) - sc-401808 from Santa Cruz Biotechnology
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T1R3 HDR Plasmid (h) - sc-401808-HDR from Santa Cruz Biotechnology
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T1R3 Double Nickase Plasmid (h) - sc-401808-NIC from Santa Cruz Biotechnology
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T1R3 Double Nickase Plasmid (h2) - sc-401808-NIC-2 from Santa Cruz Biotechnology
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T1R3 CRISPR Activation Plasmid (h) - sc-401808-ACT from Santa Cruz Biotechnology
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T1R3 CRISPR Activation Plasmid (h2) - sc-401808-ACT-2 from Santa Cruz Biotechnology
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T1R3 Lentiviral Activation Particles (h) - sc-401808-LAC from Santa Cruz Biotechnology
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T1R3 Lentiviral Activation Particles (h2) - sc-401808-LAC-2 from Santa Cruz Biotechnology
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T1R3 siRNA (h) - sc-45324 from Santa Cruz Biotechnology
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T1R3 shRNA Plasmid (h) - sc-45324-SH from Santa Cruz Biotechnology
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T1R3 shRNA (h) Lentiviral Particles - sc-45324-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU147771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21011 from Sigma-Aldrich
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TAS1R3 siRNA (Human) - CRJ3192 from Cohesion Biosciences
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TAS1R3 - MBS8230925 from MyBioSource
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T1R3 CRISPR/Cas9 KO Plasmid (h2) - sc-401808-KO-2 from Santa Cruz Biotechnology
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T1R3 HDR Plasmid (h2) - sc-401808-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TAS1R3(NM_152228.1) - SHL056701 from Creative biogene
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shRNA set against Human TAS1R1(NM_177541.1) - SHL056718 from Creative biogene
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Human TAS1R3 siRNA - orb273693 from Biorbyt
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TAS1R3 shRNA Plasmid (Human) - CHJ3192 from Cohesion Biosciences
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TAS1R3 miRNA 3'UTR clone - MiUTR1H-10189 from Creative biogene
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