HDAC2

Gene Symbol	HDAC2
Entrez Gene	3066
Alt Symbol	HD2, RPD3, YAF1
Species	Human
Gene Type	protein-coding
Description	histone deacetylase 2
Other Description	YY1-associated factor 1|transcriptional regulator homolog RPD3
Swissprots	Q92769 B4DL58 Q5SRI8 Q5SZ86 E1P561 B3KRS5 Q8NEH4
Accessions	EAW48252 EAW48253 EAW48254 EAW48255 Q92769 AA704179 AB209190 BAD92427 AK092156 BAG52487 AK097376 BAG53457 AK296856 BAG59420 AV719958 BC013141 BC031055 AAH31055 BC146376 AAI46377 BC148797 AAI48798 BM550464 BP201509 CN304190 CN315003 U31814 AAC50814 XM_011535786 XP_011534088 XM_011535787 XP_011534089 XM_011535788 XP_011534090 NM_001527 NP_001518 NR_033441 NR_073443
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. May be involved in the transcriptional repression of circadian target genes, such as PER1, mediated by CRY1 through histone deacetylation. Involved in MTA1-m
Subcellular Location	Nucleus {ECO:0000269|PubMed:24970816}. Cytoplasm {ECO:0000269|PubMed:24970816}.
Tissue Specificity	Widely expressed; lower levels in brain and lung.
Top Pathways	Viral carcinogenesis, Alcoholism, Epstein-Barr virus infection, Cell cycle, Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HDAC2 ELISA Kit (Sandwich ELISA) - LS-F6327 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat HDAC2 ELISA Kit (Cell-Based ELISA) - LS-F2038 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-HDAC2 (Ser394) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1522 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Histone Deacetylase 2/HDAC2 Colorimetric Assay Kit - KA0688 from Novus Biologicals Category Assay Kit Prices $799.00 Sizes 1 kit

Human Histone Deacetylase 2 ELISA Kit - abx151816 from Abbexa Category ELISA Kit Sensitivity 0.065 ng/ml Range 0.156 ng/ml - 10 ng/ml

Histone Deacetylase 2, HDAC2, Human, ELISA Kit - E-EL-H1337 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Histone Deacetylase 2 (HDAC2), Human, ELISA Kit - SEC210Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.065ng/mL Range 0.156-10ng/mL

Histone Deacetylase 2, Human, ELISA Kit - E01H0235 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Histone Deacetylase 2, HDAC2, Mouse, ELISA Kit - E-EL-M0120 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Histone Deacetylase 2, HDAC2, Rat, ELISA Kit - E-EL-R0972 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Histone Deacetylase 2, ELISA Kit - MBS748288 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS751638 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS062743 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS042523 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS050715 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS008238 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS084529 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS015416 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS033341 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS753217 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Histone Deacetylase 2, ELISA Kit - MBS037954 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS106307 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone Deacetylase 2, ELISA Kit - MBS007752 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

HDAC2 Colorimetric Cell-Based ELISA Kit - CB5320 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

HDAC2 (Phospho-Ser394) Colorimetric Cell-Based ELISA Kit - CBP1568 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

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