Gene Symbol |
UBA5
|
Entrez Gene |
79876
|
Alt Symbol |
THIFP1, UBE1DC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ubiquitin-like modifier activating enzyme 5
|
Other Description |
UBA5, ubiquitin-activating enzyme E1 homolog|UFM1-activating enzyme|ubiquitin-activating enzyme 5|ubiquitin-activating enzyme E1 domain-containing protein 1|ubiquitin-activating enzyme E1-domain containing 1|ubiquitin-like modifier-activating enzyme 5
|
Swissprots |
D3DNC8 Q9GZZ9 Q96ST1 A6NJL3
|
Accessions |
EAW79189 EAW79190 EAW79191 EAW79192 Q9GZZ9 AB154406 BAD15375 AK026904 BAB15587 AK027563 BAB55199 AK056238 AK129616 AK310239 AL136757 CAB66691 AL832669 AM392525 CAL37403 AM393124 CAL38002 AY253672 AAP79600 BC009737 AAH09737 BC048015 BM541647 BQ581736 BU739244 DB082596 DB457433 XM_006713752 XP_006713815 XM_011513183 XP_011511485 XM_011513184 XP_011511486 XM_011513185 XP_011511487 NM_024818 NP_079094 NM_198329 NP_938143
|
Function |
E1-like enzyme which activates UFM1 and SUMO2. {ECO:0000269|PubMed:15071506, ECO:0000269|PubMed:18442052, ECO:0000269|PubMed:20368332}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18442052}. Nucleus {ECO:0000269|PubMed:18442052}. Note=Localizes mainly in cytoplasm, while it mainly localizes to the nucleus in presence of SUMO2.
|
Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:16328888}.
|