Gene Symbol | UBA5 |
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Entrez Gene | 79876 |
Alt Symbol | THIFP1, UBE1DC1 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-like modifier activating enzyme 5 |
Other Description | UBA5, ubiquitin-activating enzyme E1 homolog|UFM1-activating enzyme|ubiquitin-activating enzyme 5|ubiquitin-activating enzyme E1 domain-containing protein 1|ubiquitin-activating enzyme E1-domain containing 1|ubiquitin-like modifier-activating enzyme 5 |
Swissprots | D3DNC8 Q9GZZ9 Q96ST1 A6NJL3 |
Accessions | EAW79189 EAW79190 EAW79191 EAW79192 Q9GZZ9 AB154406 BAD15375 AK026904 BAB15587 AK027563 BAB55199 AK056238 AK129616 AK310239 AL136757 CAB66691 AL832669 AM392525 CAL37403 AM393124 CAL38002 AY253672 AAP79600 BC009737 AAH09737 BC048015 BM541647 BQ581736 BU739244 DB082596 DB457433 XM_006713752 XP_006713815 XM_011513183 XP_011511485 XM_011513184 XP_011511486 XM_011513185 XP_011511487 NM_024818 NP_079094 NM_198329 NP_938143 |
Function | E1-like enzyme which activates UFM1 and SUMO2. {ECO:0000269|PubMed:15071506, ECO:0000269|PubMed:18442052, ECO:0000269|PubMed:20368332}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18442052}. Nucleus {ECO:0000269|PubMed:18442052}. Note=Localizes mainly in cytoplasm, while it mainly localizes to the nucleus in presence of SUMO2. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:16328888}. |
UBA5 CRISPR/Cas9 KO Plasmid (h) - sc-413282 from Santa Cruz Biotechnology
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UBA5 HDR Plasmid (h) - sc-413282-HDR from Santa Cruz Biotechnology
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UBA5 Double Nickase Plasmid (h) - sc-413282-NIC from Santa Cruz Biotechnology
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UBA5 Double Nickase Plasmid (h2) - sc-413282-NIC-2 from Santa Cruz Biotechnology
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UBA5 CRISPR Activation Plasmid (h) - sc-413282-ACT from Santa Cruz Biotechnology
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UBA5 CRISPR Activation Plasmid (h2) - sc-413282-ACT-2 from Santa Cruz Biotechnology
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UBA5 Lentiviral Activation Particles (h) - sc-413282-LAC from Santa Cruz Biotechnology
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UBA5 Lentiviral Activation Particles (h2) - sc-413282-LAC-2 from Santa Cruz Biotechnology
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UBA5 siRNA (h) - sc-78187 from Santa Cruz Biotechnology
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UBA5 shRNA Plasmid (h) - sc-78187-SH from Santa Cruz Biotechnology
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UBA5 shRNA (h) Lentiviral Particles - sc-78187-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU094721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22339 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22339 from Sigma-Aldrich
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UBA5 siRNA (Human) - CRJ2634 from Cohesion Biosciences
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UBA5 - MBS8236839 from MyBioSource |
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UBA5 - MBS8218242 from MyBioSource |
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UBA5 - MBS8241132 from MyBioSource |
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shRNA set against Human UBA5 (NM_198329.2) - SHH438672 from Creative biogene
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shRNA set against Human UBE1DC1(NM_198329.2) - SHL109722 from Creative biogene
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shRNA set against Human UBE1DC1(NM_024818.3) - SHL109740 from Creative biogene
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Human UBA5 siRNA - orb273135 from Biorbyt
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UBA5 shRNA Plasmid (Human) - CHJ2634 from Cohesion Biosciences
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UBA5 miRNA 3'UTR clone - MiUTR1H-10929 from Creative biogene
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UBA5 miRNA 3'UTR clone - MiUTR1H-10930 from Creative biogene
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