HEPACAM2

Gene Symbol	HEPACAM2
Entrez Gene	253012
Alt Symbol	MIKI
Species	Human
Gene Type	protein-coding
Description	HEPACAM family member 2
Other Description	mitotic kinetics regulator
Swissprots	B9EG93 B4DPJ1 A8MVW5 Q6UXI0 E9PDV5 B3KTT4
Accessions	A8MVW5 AK096002 BAG53196 AK298361 BAG60603 AY358345 AAQ88711 BC046365 BC136300 AAI36301 BC136301 AAI36302 BC139906 AAI39907 DA426282 H75859 XM_011516000 XP_011514302 XM_011516001 XP_011514303 NM_001039372 NP_001034461 NM_001288804 NP_001275733 NM_001288810 NP_001275739 NM_198151 NP_937794
Function	Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation. {ECO:0000269|PubMed:22864114}.
Subcellular Location	Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=In interphase, localizes to the Golgi apparatus. Localizes to centrosomes and spindles during prophase, prometaphase, and metaphase of mitosis, and to midbodies at telophase. Translocation to mitotic centrosomes is the result of poly-ADP-ribosylation (PARsylation).
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:19358830}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HEPACAM2 CRISPR/Cas9 KO Plasmid (h) - sc-417411 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 HDR Plasmid (h) - sc-417411-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 Double Nickase Plasmid (h) - sc-417411-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 Double Nickase Plasmid (h2) - sc-417411-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 CRISPR Activation Plasmid (h) - sc-417411-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 CRISPR Activation Plasmid (h2) - sc-417411-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 Lentiviral Activation Particles (h) - sc-417411-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 Lentiviral Activation Particles (h2) - sc-417411-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

HEPACAM2 siRNA (h) - sc-89610 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HEPACAM2 shRNA Plasmid (h) - sc-89610-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HEPACAM2 shRNA (h) Lentiviral Particles - sc-89610-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU010051 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9974 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9974 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06467 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr06467

HEPACAM2 siRNA (Human) - CRJ6633 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HEPACAM2 - MBS8234202 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human HEPACAM2 (NM_198151.1) - SHH311537 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human LOC253012(NM_001039372.1) - SHH153515 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human LOC253012(NM_198151.1) - SHH153533 from Creative biogene Category siRNA Species Reactivities Human

Human HEPACAM2 siRNA - orb277134 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HEPACAM2 shRNA Plasmid (Human) - CHJ6633 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

HEPACAM2 miRNA 3'UTR clone - MiUTR1H-05755 from Creative biogene Species Reactivities Human

HEPACAM2 miRNA 3'UTR clone - MiUTR1H-05756 from Creative biogene Species Reactivities Human

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