| Gene Symbol |
TYMS
|
| Entrez Gene |
7298
|
| Alt Symbol |
HST422, TMS, TS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thymidylate synthetase
|
| Other Description |
TSase|thymidylate synthase
|
| Swissprots |
Q8WYK3 P04818 Q8WYK4
|
| Accessions |
AAD43903 AAF66448 BAA00404 BAA00472 CBN68109 EAX01716 EAX01717 EAX01718 EAX01719 EAX01720 EAX01721 EAX01722 P04818 AB062290 BAB93473 AB077207 BAB83676 AB077208 BAB83677 AK223372 BAD97092 AK292620 BAF85309 AK314140 BAG36830 BC002567 AAH02567 BC013919 AAH13919 BC018858 BC083512 AAH83512 BT006811 AAP35457 DQ892149 ABM83075 X02308 CAA26178 NM_001071 NP_001062
|
| Function |
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. {ECO:0000269|PubMed:21876188}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21876188}. Cytoplasm {ECO:0000269|PubMed:21876188}. Mitochondrion {ECO:0000269|PubMed:21876188}. Mitochondrion matrix {ECO:0000269|PubMed:21876188}. Mitochondrion inner membrane {ECO:0000269|PubMed:21876188}.
|
| Top Pathways |
Pyrimidine metabolism, One carbon pool by folate
|
![Western Blot: Thymidylate Synthase Overexpression Lysate (Native) [NBP2-08333] - Thymidylate Synthase Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TYMS.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4280_Thymidylate-Synthase-Overexpression-Lysate-(Native)-Western-Blot-NBP2-08333-img0002.jpg)