| Gene Symbol |
GLRA1
|
| Entrez Gene |
2741
|
| Alt Symbol |
HKPX1, STHE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycine receptor, alpha 1
|
| Other Description |
glycine receptor 48 kDa subunit|glycine receptor strychnine-binding subunit|glycine receptor subunit alpha-1
|
| Swissprots |
Q6DJV9 B2R6T3 Q14C77 P23415
|
| Accessions |
AAB38405 EAW61656 EAW61657 P23415 AK226046 AK308539 AK312702 BAG35580 BC074980 AAH74980 BC114947 AAI14948 BC114967 AAI14968 DA749850 X52009 CAA36258 XM_005268412 XP_005268469 NM_000171 NP_000162 NM_001146040 NP_001139512 NM_001292000 NP_001278929
|
| Function |
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: Glycine Receptor Alpha 1 Overexpression Lysate (Adult Normal) [NBP2-04151] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Glycine Receptor Alpha 1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2398_Glycine%2520Receptor%2520Alpha%25201%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04151-img0001.jpg)