Gene Symbol | GLRA1 |
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Entrez Gene | 2741 |
Alt Symbol | HKPX1, STHE |
Species | Human |
Gene Type | protein-coding |
Description | glycine receptor, alpha 1 |
Other Description | glycine receptor 48 kDa subunit|glycine receptor strychnine-binding subunit|glycine receptor subunit alpha-1 |
Swissprots | Q6DJV9 B2R6T3 Q14C77 P23415 |
Accessions | AAB38405 EAW61656 EAW61657 P23415 AK226046 AK308539 AK312702 BAG35580 BC074980 AAH74980 BC114947 AAI14948 BC114967 AAI14968 DA749850 X52009 CAA36258 XM_005268412 XP_005268469 NM_000171 NP_000162 NM_001146040 NP_001139512 NM_001292000 NP_001278929 |
Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
GlyR α1 CRISPR/Cas9 KO Plasmid (h) - sc-404734 from Santa Cruz Biotechnology
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GlyR α1 HDR Plasmid (h) - sc-404734-HDR from Santa Cruz Biotechnology
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GlyR α1 Double Nickase Plasmid (h) - sc-404734-NIC from Santa Cruz Biotechnology
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GlyR α1 Double Nickase Plasmid (h2) - sc-404734-NIC-2 from Santa Cruz Biotechnology
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GlyR α1 CRISPR Activation Plasmid (h) - sc-404734-ACT from Santa Cruz Biotechnology
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GlyR α1 CRISPR Activation Plasmid (h2) - sc-404734-ACT-2 from Santa Cruz Biotechnology
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GlyR α1 Lentiviral Activation Particles (h) - sc-404734-LAC from Santa Cruz Biotechnology
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GlyR α1 Lentiviral Activation Particles (h2) - sc-404734-LAC-2 from Santa Cruz Biotechnology
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GlyR α1 siRNA (h) - sc-42467 from Santa Cruz Biotechnology
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GlyR α1 shRNA Plasmid (h) - sc-42467-SH from Santa Cruz Biotechnology
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GlyR α1 shRNA (h) Lentiviral Particles - sc-42467-V from Santa Cruz Biotechnology
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Glycine Receptor Alpha 1 RNAi - H00002741-R01 from Novus Biologicals
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MISSION® esiRNA - EHU049691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1935 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1935 from Sigma-Aldrich
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GLRA1 siRNA (Human) - CRH1825 from Cohesion Biosciences
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GLRA1 - MBS8232005 from MyBioSource
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shRNA set against Human Glra1 (NM_000171.3) - SHH301926 from Creative biogene
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Human GLRA1 siRNA - orb262327 from Biorbyt
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GLRA1 shRNA Plasmid (Human) - CHH1825 from Cohesion Biosciences
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GLRA1 miRNA 3'UTR clone - MiUTR3H-00926 from Creative biogene
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GLRA1 miRNA 3'UTR clone - MiUTR3H-00927 from Creative biogene
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