LPAR6

Gene Symbol LPAR6
Entrez Gene 10161
Alt Symbol ARWH1, HYPT8, LAH3, P2RY5, P2Y5
Species Human
Gene Type protein-coding
Description lysophosphatidic acid receptor 6
Other Description G-protein coupled purinergic receptor P2Y5|LPA receptor 6|LPA-6|P2Y purinoceptor 5|RB intron encoded G-protein coupled receptor|oleoyl-L-alpha-lysophosphatidic acid receptor|purinergic receptor 5|purinergic receptor P2Y G protein-coupled protein 5|purinergic receptor P2Y, G-protein coupled, 5
Swissprots Q7Z3S0 O15133 A4FTW9 Q3KPF5 F2YGU4 Q7Z3S6 Q5VW44 P43657 Q53FA0 B3KVF2
Accessions AAL40065 AAN64134 EAX08796 EAX08797 P43657 AF000546 AAB62190 AK122856 BAG53764 AK123059 BAG53867 AK223389 BAD97109 BC039373 BC040850 AAH40850 BC045651 AAH45651 BC054346 BC070295 AAH70295 BC106756 AAI06757 BF950635 BF951153 BQ006077 BX537392 CAD97634 BX537438 CAD97680 BX537445 CAD97687 BX647109 EU831916 ACE87357 EU832010 ACE86673 HQ995530 ADZ31975 JF810890 AEP43757 NM_001162497 NP_001155969 NM_001162498 NP_001155970 NM_005767 NP_005758
Function Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture. {ECO:0000269|PubMed:18297070}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:18297070}; Multi-pass membrane protein {ECO:0000269|PubMed:18297070}.
Tissue Specificity Expressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes. {ECO:0000269|PubMed:11004484, ECO:0000269|PubMed:18297070, ECO:0000269|PubMed:18297072}.
Top Pathways PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction

P2Y5 (A-19) - sc-15212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

P2Y5 (H-60) - sc-20126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
P2Y5 (H-60): sc-20126. Western blot analysis of P2Y5 expression in Hs 732.Sk/Mu whole cell lysate.

P2Y5 (C-20) - sc-15214 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-P2RY5 antibody - ab85894 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-P2RY5 antibody - ab113055 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-P2RY5 antibody (ab113055) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142, AP) - LS-C262097 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142, APC) - LS-C262098 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142, Biotin) - LS-C262099 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142, FITC) - LS-C262100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142, Azide-free, HRP) - LS-C262101 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa266-315) - LS-C152207 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LPAR6 / P2RY5 / P2Y5 antibody Western Blot of Fetal Heart.

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142, PE) - LS-C262102 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa113-142) - LS-C329779 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (C-Terminus) IHC-plus™ - LS-A852 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa85-134) - LS-C205862 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LPAR6 / P2RY5 / P2Y5 antibody Western Blot of HeLa. Antibody dilution: 1 ug/ml.

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (aa106-134) - LS-C165848 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LPAR6 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-LPAR6 / P2RY5 / P2Y5 Antibody (Extracellular Domain) IHC-plus™ - LS-A850 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPAR6 / P2RY5 antibody LS-A850 IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

P2RY5 Antibody - NBP2-29372 from Novus Biologicals

Prices $499.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western Blot: P2RY5 Antibody [NBP2-29372] - analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the LPAR6 antibody detected the LPAR6 protein (arrow).

P2RY5 Antibody - NBP1-30743 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LPAR6/P2RY5 Antibody - NBP2-14197 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LPAR6/P2RY5 Antibody - NLS850 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

LPAR6/P2RY5 Antibody - NLS852 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: P2RY5 Antibody [NLS852] - Analysis of anti-P2RY5 antibody with human pancreas.

Anti-LPAR6 / P2RY5 antibody produced in rabbit - SAB2900659 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LPAR6/P2RY5 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900659</B>: Anti-LPAR6/P2RY5 antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ANTI-LPAR6 (CENTER) antibody produced in rabbit - SAB1301549 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>LPAR6 (Center): <B>Cat. No. SAB1301549</B>: LPAR6 in Human breast carcinoma tissue with LPAR6 antibody (Center) at 12.5 μg/mL.

Anti-LPAR6 antibody produced in rabbit - HPA028934 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LPAR6:<B>Cat. No. HPA028934</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.
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