| Gene Symbol |
MED29
|
| Entrez Gene |
55588
|
| Alt Symbol |
IXL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 29
|
| Other Description |
intersex-like protein|mediator of RNA polymerase II transcription subunit 29
|
| Swissprots |
Q9NTF4 Q9NX70 Q5XX09 M0R2E4 B4DNQ6
|
| Accessions |
EAW56884 Q9NX70 AK000411 BAA91147 AK026527 AK090877 AK092909 AK124629 AK294667 BAG57835 AK297772 BAG60118 AK298014 BAG60318 AK300563 BAG62269 AK316010 BAH14381 AL137304 CAB70687 AY729650 AAU43732 BC019015 AAH19015 NM_017592 NP_060062
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:15555573}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:15555573}.
|
| Tissue Specificity |
Widely expressed in embryo and adult. {ECO:0000269|PubMed:15555573}.
|
![Western Blot: MED29 Overexpression Lysate (Adult Normal) [NBP2-06959] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MED29.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4919_MED29%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06959-img0001.jpg)