Gene Symbol | MED29 |
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Entrez Gene | 55588 |
Alt Symbol | IXL |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 29 |
Other Description | intersex-like protein|mediator of RNA polymerase II transcription subunit 29 |
Swissprots | Q9NTF4 Q9NX70 Q5XX09 M0R2E4 B4DNQ6 |
Accessions | EAW56884 Q9NX70 AK000411 BAA91147 AK026527 AK090877 AK092909 AK124629 AK294667 BAG57835 AK297772 BAG60118 AK298014 BAG60318 AK300563 BAG62269 AK316010 BAH14381 AL137304 CAB70687 AY729650 AAU43732 BC019015 AAH19015 NM_017592 NP_060062 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:15555573}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15555573}. |
Tissue Specificity | Widely expressed in embryo and adult. {ECO:0000269|PubMed:15555573}. |
Med29 CRISPR/Cas9 KO Plasmid (h) - sc-409289 from Santa Cruz Biotechnology
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Med29 HDR Plasmid (h) - sc-409289-HDR from Santa Cruz Biotechnology
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Med29 Double Nickase Plasmid (h) - sc-409289-NIC from Santa Cruz Biotechnology
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Med29 Double Nickase Plasmid (h2) - sc-409289-NIC-2 from Santa Cruz Biotechnology
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Med29 CRISPR Activation Plasmid (h) - sc-409289-ACT from Santa Cruz Biotechnology
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Med29 CRISPR Activation Plasmid (h2) - sc-409289-ACT-2 from Santa Cruz Biotechnology
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Med29 Lentiviral Activation Particles (h) - sc-409289-LAC from Santa Cruz Biotechnology
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Med29 Lentiviral Activation Particles (h2) - sc-409289-LAC-2 from Santa Cruz Biotechnology
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Med29 siRNA (h) - sc-97527 from Santa Cruz Biotechnology
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Med29 shRNA Plasmid (h) - sc-97527-SH from Santa Cruz Biotechnology
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Med29 shRNA (h) Lentiviral Particles - sc-97527-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU137631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13178 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13178 from Sigma-Aldrich
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MED29 siRNA (Human) - CRJ0755 from Cohesion Biosciences
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shRNA set against Human MED29 (NM_017592.1) - SHH340083 from Creative biogene
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shRNA set against Human IXL(NM_017592.1) - SHH137783 from Creative biogene
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MED29 shRNA Plasmid (Human) - CHJ0755 from Cohesion Biosciences
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MED29 miRNA 3'UTR clone - MiUTR1H-05057 from Creative biogene
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