Gene Symbol | TMEM97 |
---|---|
Entrez Gene | 27346 |
Alt Symbol | MAC30 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 97 |
Other Description | - |
Swissprots | B4DS02 Q07823 Q5BJF2 |
Accessions | EAW51067 EAW51068 EAW51069 Q5BJF2 AK293331 BAG56847 AK299511 BAG61464 AK307678 BC017362 BC045655 AAH45655 BC091504 AAH91504 CA441136 DA410183 L19183 AAA16188 XM_005257965 XP_005258022 NM_014573 NP_055388 |
Function | Plays a role as a regulator of cellular cholesterol homeostasis. {ECO:0000269|PubMed:19583955}. |
Subcellular Location | Nucleus membrane. Rough endoplasmic reticulum. Cell membrane. Lysosome. Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Note=Localized in sterol- depleted cells at cell membrane and in lysosomes. |
Tissue Specificity | Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells and meningioma cancers. Expressed in ovarian cancer; expression is reduced relative to OSE cells. {ECO:0000269|PubMed:15375745, ECO:0000269|PubMed:18070364, ECO:0000269|PubMed:7694637}. |
TMEM97 CRISPR/Cas9 KO Plasmid (h) - sc-411997 from Santa Cruz Biotechnology
|
||||||||
TMEM97 HDR Plasmid (h) - sc-411997-HDR from Santa Cruz Biotechnology
|
||||||||
TMEM97 Double Nickase Plasmid (h) - sc-411997-NIC from Santa Cruz Biotechnology
|
||||||||
TMEM97 Double Nickase Plasmid (h2) - sc-411997-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TMEM97 CRISPR Activation Plasmid (h) - sc-411997-ACT from Santa Cruz Biotechnology
|
||||||||
TMEM97 CRISPR Activation Plasmid (h2) - sc-411997-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TMEM97 Lentiviral Activation Particles (h) - sc-411997-LAC from Santa Cruz Biotechnology
|
||||||||
TMEM97 Lentiviral Activation Particles (h2) - sc-411997-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TMEM97 siRNA (h) - sc-93890 from Santa Cruz Biotechnology
|
||||||||
TMEM97 shRNA Plasmid (h) - sc-93890-SH from Santa Cruz Biotechnology
|
||||||||
TMEM97 shRNA (h) Lentiviral Particles - sc-93890-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21688 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21688 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10680 from Sigma-Aldrich
|
||||||||
TMEM97 siRNA (Human) - CRH9095 from Cohesion Biosciences
|
||||||||
TMEM97 - MBS8235226 from MyBioSource
|
||||||||
shRNA set against Human TMEM97(NM_014573.2) - SHL081818 from Creative biogene
|
||||||||
Human TMEM97 siRNA - orb269597 from Biorbyt
|
||||||||
TMEM97 shRNA Plasmid (Human) - CHH9095 from Cohesion Biosciences
|
||||||||
TMEM97 miRNA 3'UTR clone - MiUTR3H-12683 from Creative biogene
|