C6orf25

Gene Symbol C6orf25
Entrez Gene 80739
Alt Symbol G6b, NG31
Species Human
Gene Type protein-coding
Description chromosome 6 open reading frame 25
Other Description G6B|immunoglobulin receptor|protein G6b
Swissprots Q96A87 B0V024 Q96A91 A2BEZ1 A2BEZ4 Q96A90 Q96A86 Q14CK2 Q96A88 Q96A89 A2BEZ3 A2BEZ2 B0UXC8 B0V026 A2BEZ5 B0UXC4 B0UXC7 O95866
Accessions AAD18075 BAB63378 CAB46080 EAX03492 EAX03493 EAX03494 EAX03495 EAX03496 EAX03497 EAX03498 EAX03499 O95866 AJ292259 CAC83497 AJ292260 CAC83496 AJ292261 CAC83498 AJ292262 CAC83502 AJ292263 CAC83499 AJ292264 CAC83500 AJ292265 CAC83501 AK092392 BAG52544 BC111842 AAI11843 BC113719 AAI13720 BC113721 AAI13722 BC143850 AAI43851 BU681844 HQ258117 ADR82871 XM_011514920 XP_011513222 XM_011514921 XP_011513223 XM_011547318 XP_011545620 XM_011547319 XP_011545621 XM_011547719 XP_011546021 XM_011547720 XP_011546022 XM_011548105 XP_011546407 XM_011548106 XP_011546408 XM_011548304 XP_011546606 XM_011548305 XP_011546607 XM_011548306 XP_011546608 XM_011548489 XP_011546791 XM_011548490 XP_011546792 NM_025260 NP_079536 NM_138272 NP_612116 NM_138273 NP_612117 NM_138274 NP_612118 NM_138275 NP_612119 NM_138277 NP_612121 NM_138276
Function Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart. {ECO:0000269|PubMed:17311996}.
Subcellular Location Isoform B: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in a restricted set of hematopoietic cell lines including the erythroleukemia cell line K-562 and the T-cell leukemia cell lines MOLT-4 and Jurkat. Not detected in the monocyte-like cell line U-937, the B-cell-like cell line Raji, the fibroblast cell lines TK and HeLa, or the natural killer cell lines NKL, NK 62 and YT. Expressed in platelets. {ECO:0000269|PubMed:11544253, ECO:0000269|PubMed:17311996}.

G6b (S-15) - sc-161615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-C6orf25 antibody - ab69175 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-C6orf25 antibody (ab69175) at 1/500 dilutionLane 1 : C6orf25 transfected 293T lysateLane 2 : Non-transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-C6orf25 antibody - ab72535 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C6orf25 antibody (ab72535) at 2 µg/mlLane 1 : K562 cell lysate Lane 2 : K562 cell lysate with immunising peptide

Anti-C6orf25 Antibody (aa1-50) - LS-C47372 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of human G6Bin K562 cell lysate in the 1) absence and 2) presence of immunizing peptide using antibody at2 ug/ml.

Anti-C6orf25 Antibody (N-Terminus) - LS-C81491 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-C6orf25 Antibody (aa170-220) - LS-C148405 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of G6B in platelets in the 1) absence and 2) presence of immunizing peptide using LS-C148405 at 0.5 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

G6b/C6orf25 Antibody - NBP2-24647 from Novus Biologicals

Prices $269.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: C6orf25 Antibody [NBP2-24647] - analysis of G6B in platelets in the 1) absence and 2) presence of immunizing peptide using this antibody. 5 ug/ml. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

G6b/C6orf25 Antibody - NBP2-24505 from Novus Biologicals

Prices $259.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: C6orf25 Antibody [NBP2-24505] - Analysis of human G6B in K562 cell lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24505 at 2 ug/ml.

G6b/C6orf25 Antibody - NBP1-69388 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

G6b/C6orf25 Antibody - H00080739-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: G6b/C6orf25 Antibody [H00080739-B01] - analysis of C6orf25 expression in transfected 293T cell line by C6orf25 MaxPab polyclonal antibody (B01). Lane1: C6orf25 transfected lysate (25.00 KDa). Lane2: Non-transfected lysate.

C6orf25 Polyclonal Antibody - bs-15245R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Mouse Testis lysates probed with Anti-C6orf25 Polyclonal Antibody, Unconjugated (bs-15245R) at 1:300 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 90min in 37˚C

C6orf25 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15245R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15245R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15245R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15245R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, Cy3 Conjugated - bs-15245R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, Cy5 Conjugated - bs-15245R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, Cy5.5 Conjugated - bs-15245R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, Cy7 Conjugated - bs-15245R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, FITC Conjugated - bs-15245R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-C6orf25 Polyclonal Antibody, PE Conjugated - bs-15245R-PE from Bioss

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, Biotin Conjugated - bs-15245R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C6orf25 Polyclonal Antibody, HRP Conjugated - bs-15245R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C6orf25 (196-207) antibody produced in rabbit - SAB1102969 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C6orf25 was separated on SDS-PAGE, blotted with Anti-C6orf25 (196-207) (<B>Cat. No. SAB1102969</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-C6ORF25 antibody produced in rabbit - SAB2100314 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C6ORF25: <B>Cat. No.SAB2100314</B>: C6orf25 in Jurkat cell lysate with C6orf25 antibody at 1.0 μg/mL.
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