CYP2F1

Gene Symbol CYP2F1
Entrez Gene 1572
Alt Symbol C2F1, CYP2F
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily F, polypeptide 1
Other Description CYPIIF1|cytochrome P450 2F1|cytochrome P450, subfamily IIF, polypeptide 1|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots A7KAU6 Q8WWJ2 A7KAV0 P24903 A7KAU9 A7KAU8 A7KAU7 Q32MN5
Accessions AAL69652 ABO41974 ABO41975 ABO41976 ABO41977 ABO41978 ABO41979 ABO41980 EAW57017 EAW57018 P24903 AK296884 BAG59445 AK298082 BAG60369 AK316498 BAH14869 BC109056 AAI09057 BC109057 J02906 AAA52156 XM_006723053 XP_006723116 XM_011526551 XP_011524853 XM_011526552 XP_011524854 XM_011526553 XP_011524855 XM_011526554 XP_011524856 XM_011526555 XP_011524857 XR_430190 XR_935755 XR_935756 NM_000774 NP_000765
Function May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. {ECO:0000269|PubMed:1974816}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305|PubMed:10383923}; Peripheral membrane protein {ECO:0000305|PubMed:10383923}. Microsome membrane {ECO:0000269|PubMed:10383923}; Peripheral membrane protein {ECO:0000269|PubMed:10383923}.
Tissue Specificity Expressed in lung. Rarely detected in liver and placenta. {ECO:0000269|PubMed:1974816, ECO:0000269|PubMed:8619884}.
Top Pathways Metabolism of xenobiotics by cytochrome P450

CYP2F1 (H-41) - sc-67282 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP2F1 (H-41): sc-67282. Western blot analysis of CYP2F1 expression in WI 38 whole cell lysate (A) and rat lung (B) and mouse lung (C) tissue extracts.

CYP2F1 (E-10) - sc-377499 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2F1 (E-10): sc-377499. Western blot analysis of CYP2F2 expression in non-transfected: sc-117752 (A) and mouse CYP2F2 transfected: sc-126691 (B) 293T whole cell lysates.

CYP2F1 (Q-15) - sc-66360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2F1 (Q-15): sc-66360. Western blot analysis of CYP2F1 expression in HeLa whole cell lysate.

CYP2F2 (F-9) - sc-374540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2F2 (F-9): sc-374540. Western blot analysis of CYP2F2 expression in non-transfected: sc-117752 (A) and mouse CYP2F2 transfected: sc-126690 (B) 293T whole cell lysates.

CYP2F2 (E-7) - sc-374470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2F2 (E-7): sc-374470. Western blot analysis of CYP2F2 expression in non-transfected: sc-117752 (A) and mouse CYP2F2 transfected: sc-126690 (B) 293T whole cell lysates.

CYP2F2 (M-74) - sc-67283 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP2F2 (M-74): sc-67283. Western blot analysis of CYP2F2 expression in mouse lung tissue extract.

Anti-CYP2F1 antibody - C-terminal - ab135815 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP2F1 antibody - C-terminal (ab135815) at 1/50 dilution + A2058 cell line lysates at 35 µg

Anti-CYP2F / CYP2F1 Antibody - LS-C332463 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse lung cell line, using CYP2F1 antibody.

Anti-CYP2F / CYP2F1 Antibody (C-Terminus) - LS-C97497 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP2F1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CYP2F / CYP2F1 Antibody IHC-plus™ - LS-B10872 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYP2F / CYP2F1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10872 concentration 7.5 ug/ml.

CYP2F1 Antibody - NBP2-14922 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP2F1 Antibody [NBP2-14922] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE; antibody diluted at 1:1000.

CYP2F1 Antibody - H00001572-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-CYP2F1 (C-term) antibody produced in rabbit - SAB1300943 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>ANTI-CYP2F1 (C-Term) Antibody: <B>Cat. No. SAB1300943</B>: CYP2F1 in human lung carcinoma tissue with ANTI-CYP2F1 (C-Term) at 40 μg/mL.

Anti-CYP2F1 antibody produced in rabbit - SAB2700551 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP2F1: <B>Cat. No. SAB2700551</B>: Western Blot analysis of CYP2F1 in extracts from <B>Lanes</B><BR/>A. A549 using <B>Cat. No. SAB2700551</B> at a 1:1000 dilution.

CP2F1 Antibody - N-terminal region (ARP76069_P050) - ARP76069_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CYP2F1-Antibody-C-term - AP7883b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CYP2F1 Antibody (C-term) (Cat. #AP7883b) in A2058 cell line lysates (35ug/lane).CYP2F1 (arrow) was detected using the purified Pab.

CYP2F1 Antibody - C-terminal region (OAAB04958) - OAAB04958 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CYP2F1 antibody [N1C1] - GTX117184 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CYP2F1 antibody [N1C1] used in Western blot. GTX117184

Anti -CYP2F1 (Cytochrome P450 2F1, C2F1, CYP2F) - 210381 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

CYP2F1 Polyclonal Antibody - A3292 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse lung cell line, using CYP2F1 antibody.

CYP2F1 Polyclonal Antibody - A7550 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using CYP2F1 antibody.

CYP2F1 antibody - 70R-16712 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

CYP2F1 Antibody - abx111924 from Abbexa

Host Rabbit
Clonality Polyclonal

CYP2F1 Antibody - abx002340 from Abbexa

Host Rabbit
Clonality Polyclonal

CYP2F1 antibody - 21579-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse lung tissue were subjected to SDS PAGE followed by western blot with 21579-1-AP(CYP2F1 antibody) at dilution of 1:500
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