CYP2F1

Gene Symbol	CYP2F1
Entrez Gene	1572
Alt Symbol	C2F1, CYP2F
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 2, subfamily F, polypeptide 1
Other Description	CYPIIF1|cytochrome P450 2F1|cytochrome P450, subfamily IIF, polypeptide 1|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots	A7KAU6 Q8WWJ2 A7KAV0 P24903 A7KAU9 A7KAU8 A7KAU7 Q32MN5
Accessions	AAL69652 ABO41974 ABO41975 ABO41976 ABO41977 ABO41978 ABO41979 ABO41980 EAW57017 EAW57018 P24903 AK296884 BAG59445 AK298082 BAG60369 AK316498 BAH14869 BC109056 AAI09057 BC109057 J02906 AAA52156 XM_006723053 XP_006723116 XM_011526551 XP_011524853 XM_011526552 XP_011524854 XM_011526553 XP_011524855 XM_011526554 XP_011524856 XM_011526555 XP_011524857 XR_430190 XR_935755 XR_935756 NM_000774 NP_000765
Function	May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. {ECO:0000269|PubMed:1974816}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000305|PubMed:10383923}; Peripheral membrane protein {ECO:0000305|PubMed:10383923}. Microsome membrane {ECO:0000269|PubMed:10383923}; Peripheral membrane protein {ECO:0000269|PubMed:10383923}.
Tissue Specificity	Expressed in lung. Rarely detected in liver and placenta. {ECO:0000269|PubMed:1974816, ECO:0000269|PubMed:8619884}.
Top Pathways	Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYP2F1 protein fragment - ab158255 from Abcam Category Protein Source Wheat germ Species Human

CYP2F / CYP2F1 Antibody Blocking Peptide - LS-E9344 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CYP2F1 Protein - H00001572-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CYP2F1-Antibody-C-term-Blocking-Peptide - BP7883b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP2F1 - H00001572-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CYP2F1 - H00001572-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CYP2F1 fusion protein - Ag16124 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CYP2F1 fusion protein - Ag17081 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CYP2F1, GST-tagged - CYP2F1-11776H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Cytochrome P450 2F1(CYP2F1) - CSB-YP006426HU CSB-EP006426HU CSB-BP006426HU CSB-MP006426HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CYP2F1 Protein - abx163410 from Abbexa Category Protein Species Human, Mouse, Rat

CYP2F1-Antibody-Center-Blocking-Peptide - BP7883c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP2F1 Peptide, Human - M34GP03962H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cytochrome P450 2F1 (CYP2F1), Recombinant Protein - MBS953523 from MyBioSource Category Protein Prices $1,275.00, $1,275.00, $1,495.00, $1,495.00, $2,090.00, $2,090.00, $2,555.00, $2,555.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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