| Gene Symbol |
MARCH11
|
| Entrez Gene |
441061
|
| Alt Symbol |
MARCH-XI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
membrane-associated ring finger (C3HC4) 11
|
| Other Description |
E3 ubiquitin-protein ligase MARCH11|membrane-associated RING finger protein 11|membrane-associated RING-CH protein XI
|
| Swissprots |
A6NNE9 A7E2S6
|
| Accessions |
A6NNE9 BC150513 AAI50514 BC150514 AAI50515 DB455291 NM_001102562 NP_001096032
|
| Function |
E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|