Gene Symbol | MARCH11 |
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Entrez Gene | 441061 |
Alt Symbol | MARCH-XI |
Species | Human |
Gene Type | protein-coding |
Description | membrane-associated ring finger (C3HC4) 11 |
Other Description | E3 ubiquitin-protein ligase MARCH11|membrane-associated RING finger protein 11|membrane-associated RING-CH protein XI |
Swissprots | A6NNE9 A7E2S6 |
Accessions | A6NNE9 BC150513 AAI50514 BC150514 AAI50515 DB455291 NM_001102562 NP_001096032 |
Function | E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
MARCH11 CRISPR/Cas9 KO Plasmid (h) - sc-416041 from Santa Cruz Biotechnology
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MARCH11 HDR Plasmid (h) - sc-416041-HDR from Santa Cruz Biotechnology
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MARCH11 Double Nickase Plasmid (h) - sc-416041-NIC from Santa Cruz Biotechnology
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MARCH11 Double Nickase Plasmid (h2) - sc-416041-NIC-2 from Santa Cruz Biotechnology
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MARCH11 CRISPR Activation Plasmid (h) - sc-416041-ACT from Santa Cruz Biotechnology
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MARCH11 CRISPR Activation Plasmid (h2) - sc-416041-ACT-2 from Santa Cruz Biotechnology
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MARCH11 Lentiviral Activation Particles (h) - sc-416041-LAC from Santa Cruz Biotechnology
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MARCH11 Lentiviral Activation Particles (h2) - sc-416041-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13030 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13030 from Sigma-Aldrich
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MARCH11 siRNA (Human) - CRJ8279 from Cohesion Biosciences
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shRNA set against Human March11 (NM_001102562.1) - SHH338251 from Creative biogene
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MARCH11 shRNA Plasmid (Human) - CHJ8279 from Cohesion Biosciences
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MARCH11 miRNA 3'UTR clone - MiUTR4H-TG05374 from Creative biogene
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