| Gene Symbol |
NME3
|
| Entrez Gene |
4832
|
| Alt Symbol |
DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NME/NM23 nucleoside diphosphate kinase 3
|
| Other Description |
NDK 3|NDP kinase 3|NDP kinase C|non-metastatic cells 3, protein expressed in|nucleoside diphosphate kinase 3|nucleoside diphosphate kinase C
|
| Swissprots |
Q9BWH4 Q13232
|
| Accessions |
AAK61291 CAB72319 EAW85629 Q13232 AK308663 BC000250 AAH00250 BG911570 DQ892515 ABM83441 EU176697 ABW03498 U29656 AAA85097 XM_005255332 XP_005255389 XM_011522503 XP_011520805 XM_011522504 XP_011520806 NM_002513 NP_002504
|
| Function |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
|
| Top Pathways |
Purine metabolism, Pyrimidine metabolism
|