Gene Symbol | NME3 |
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Entrez Gene | 4832 |
Alt Symbol | DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2 |
Species | Human |
Gene Type | protein-coding |
Description | NME/NM23 nucleoside diphosphate kinase 3 |
Other Description | NDK 3|NDP kinase 3|NDP kinase C|non-metastatic cells 3, protein expressed in|nucleoside diphosphate kinase 3|nucleoside diphosphate kinase C |
Swissprots | Q9BWH4 Q13232 |
Accessions | AAK61291 CAB72319 EAW85629 Q13232 AK308663 BC000250 AAH00250 BG911570 DQ892515 ABM83441 EU176697 ABW03498 U29656 AAA85097 XM_005255332 XP_005255389 XM_011522503 XP_011520805 XM_011522504 XP_011520806 NM_002513 NP_002504 |
Function | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis. |
Top Pathways | Purine metabolism, Pyrimidine metabolism |
nm23-H3 CRISPR/Cas9 KO Plasmid (h) - sc-407148 from Santa Cruz Biotechnology
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nm23-H3 HDR Plasmid (h) - sc-407148-HDR from Santa Cruz Biotechnology
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nm23-H3 Double Nickase Plasmid (h) - sc-407148-NIC from Santa Cruz Biotechnology
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nm23-H3 Double Nickase Plasmid (h2) - sc-407148-NIC-2 from Santa Cruz Biotechnology
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nm23-H3 CRISPR Activation Plasmid (h) - sc-407148-ACT from Santa Cruz Biotechnology
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nm23-H3 CRISPR Activation Plasmid (h2) - sc-407148-ACT-2 from Santa Cruz Biotechnology
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nm23-H3 Lentiviral Activation Particles (h) - sc-407148-LAC from Santa Cruz Biotechnology
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nm23-H3 Lentiviral Activation Particles (h2) - sc-407148-LAC-2 from Santa Cruz Biotechnology
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nm23-H3 siRNA (h) - sc-61205 from Santa Cruz Biotechnology
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nm23-H3 shRNA Plasmid (h) - sc-61205-SH from Santa Cruz Biotechnology
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nm23-H3 shRNA (h) Lentiviral Particles - sc-61205-V from Santa Cruz Biotechnology
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NME3 RNAi - H00004832-R03 from Novus Biologicals
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MISSION® esiRNA - EHU121521 from Sigma-Aldrich
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MISSION® siRNA - SIHK1428 from Sigma-Aldrich
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MISSION® siRNA - SIHK1426 from Sigma-Aldrich
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MISSION® siRNA - SIHK1427 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15369 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15369 from Sigma-Aldrich
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NME3 siRNA (Human) - CRH3209 from Cohesion Biosciences
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shRNA set against Human NME3 (NM_002513.2) - SHH353160 from Creative biogene
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shRNA set against Human NME3(NM_002513.2) - SHR013768 from Creative biogene
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Human NME3 siRNA - orb263711 from Biorbyt
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NME3 shRNA Plasmid (Human) - CHH3209 from Cohesion Biosciences
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NME3 miRNA 3'UTR clone - MiUTR1H-06814 from Creative biogene
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