Gene Symbol | AP4B1 |
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Entrez Gene | 10717 |
Alt Symbol | BETA-4, CPSQ5, SPG47 |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 4, beta 1 subunit |
Other Description | AP-4 adaptor complex subunit beta|AP-4 complex subunit beta-1|adaptor-related protein complex 4 subunit beta-1|beta 4 subunit of AP-4|beta4-adaptin|spastic paraplegia 47 |
Swissprots | Q96CL6 B7Z4X3 Q59EJ4 Q9Y6B7 |
Accessions | EAW56578 EAW56579 EAW56580 EAW56581 Q9Y6B7 AB209817 BAD93054 AF092094 AAD20448 AI431352 AK001045 AK057567 AK093740 BAG52756 AK298037 BAH12709 AK300204 BAG61975 AK314641 BAG37203 AW072594 BC014146 AAH14146 BG718098 DC299853 DC367373 DC368382 DC390197 HY012945 JF432293 ADZ15510 XM_005270381 XP_005270438 XM_005270382 XP_005270439 XM_011540523 XP_011538825 XM_011540524 XP_011538826 XM_011540525 XP_011538827 XM_011540526 XP_011538828 XM_011540527 XP_011538829 XM_011540528 XP_011538830 XR_246227 XR_246228 NM_001253852 NP_001240781 NM_001253853 NP_001240782 NM_001308312 NP_001295241 NM_006594 NP_006585 |
Function | Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. |
Subcellular Location | Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:22472443}. Membrane, coated pit {ECO:0000250}. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells. |
Tissue Specificity | Widely expressed. |
Top Pathways | Lysosome |
Human AP4B1 protein fragment - ab161120 from Abcam
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AP4B1 Antibody Blocking Peptide - LS-E4894 from LifeSpan Bioscience
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AP4B1 Antibody Blocking Peptide - LS-E24584 from LifeSpan Bioscience
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Recombinant Human AP4B1 Protein - H00010717-Q01 from Novus Biologicals
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AP4B1-Antibody-Center-Blocking-Peptide - BP17275c from Abgent, a WuXi AppTec company
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TUBB3 protein (His tag) - 80R-2700 from Fitzgerald
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AP4 complex subunit beta-1 - H00010717-Q01-10 from Acris Antibodies
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AP4 complex subunit beta-1 - H00010717-Q01-25 from Acris Antibodies
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AP4B1 fusion protein - ag9348 from Proteintech Group
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TUBB3 Human - PRPS-1395 from NeoScientific
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Recombinant Human AP4B1, GST-tagged - AP4B1-9725H from Creative Biomart
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Recombinant Human AP-4 complex subunit beta-1(AP4B1) - CSB-YP897585HU CSB-EP897585HU CSB-BP897585HU CSB-MP897585HU from Cusabio
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AP-4 complex subunit beta-1 (AP4B1) , Recombinant Protein - MBS1340059 from MyBioSource
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AP4B1 Protein - NBP1-88658PEP from Novus Biologicals
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AP4B1 Recombinant Protein Antigen - NBP1-88657PEP from Novus Biologicals
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AP4B1 Protein - NBP1-88656PEP from Novus Biologicals
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AP4B1 Peptide, Human - M34GP00729H from Creative Peptides
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TuBB3 - PAT-81995-1 from Nordic BioSite
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TuBB3 - PAT-81995-2 from Nordic BioSite
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