CDKN3

Gene Symbol CDKN3
Entrez Gene 1033
Alt Symbol CDI1, CIP2, KAP, KAP1
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase inhibitor 3
Other Description CDK2-associated dual specificity phosphatase|CDK2-associated dual-specificity phosphatase|Cdk-associated protein phosphatase|cyclin-dependent kinase interacting protein 2|cyclin-dependent kinase interactor 1|cyclin-dependent kinase-interacting protein 2|kinase associated phosphatase|kinase-associated phosphatase
Swissprots Q9BY36 Q99585 Q9C051 Q9C053 Q9C047 Q9C042 Q9C049 Q9BPW7 Q5U0M4 Q9C046 Q53ZU6 Q6P1N8 Q16667
Accessions AAN86348 EAW80632 EAW80633 EAW80634 Q16667 AF213033 AAK06365 AF213034 AAK06366 AF213035 AAK06367 AF213036 AAK06368 AF213037 AAK06369 AF213038 AAK06370 AF213039 AAK06371 AF213040 AAK06372 AF213041 AAK06373 AF213042 AAK06374 AF213043 AF213044 AAK06375 AF213045 AAK06376 AF213046 AAK06377 AF213047 AAK06378 AF213048 AAK06379 AF213049 AAK06380 AF213050 AAK06381 AF213051 AAK06382 AF213052 AAK06383 AF213053 AAK06384 AK098653 AK293265 BAH11478 AY257474 AAP13062 AY257475 AAP13063 AY257476 AAP13064 AY257477 AAP13065 AY257478 AAP13066 AY257479 AAP13067 BC064965 AAH64965 BC103633 AAI03634 BT019451 AAV38258 CR407666 CAG28594 EF560750 ABQ59060 L25876 AAA60222 L27711 AAA66496 U02681 AAC04932 XM_011536353 XP_011534655 NM_001130851 NP_001124323 NM_005192 NP_005183
Function May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner. {ECO:0000269|PubMed:7569954, ECO:0000269|PubMed:8127873, ECO:0000269|PubMed:8242750}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:10669749}.

CDKN3 (C-18) - sc-475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CDKN3 (C-18): sc-475. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tumor showing cytoplasmic staining.

CDKN3 (S-15) - sc-34165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CDKN3 (39) - sc-135864 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
CDKN3 (39): sc-135864. Western blot analysis of CDKN3 expression in MDCK whole cell lysate.

Anti-CDKN3 antibody - ab175393 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab175393. Blue DAPI for nuclear staining.

Anti-CDKN3 antibody - ab167517 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CDKN3 antibody (ab167517) at 1 µg/mlLane 1 : CDKN3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-CDKN3 antibody [2H10] - ab119242 from Abcam

Host Mouse
Clonality Monoclonal
Clone 2H10
All lanes : Anti-CDKN3 antibody [2H10] (ab119242) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control Lane 2 : HEK293T cells transfected with pCMV6-ENTRY CDKN3 Lysates/proteins at 5 µg per lane.

Anti-CDKN3 antibody [4D8] - ab127986 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D8
All lanes : Anti-CDKN3 antibody [4D8] (ab127986) at 1/200 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNA Lane 2 : HEK293T cells transfected with pCMV6-ENTRY CDKN3 cDNA Lysates/proteins at 5 µg per lane.

Anti-CDKN3 / KAP Antibody (clone 2E11) IHC-plus™ - LS-B11854 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E11
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-CDKN3 / KAP Antibody (aa67-116) - LS-C145708 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CDKN3 antibody LS-C145708 Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.

Anti-CDKN3 / KAP Antibody (aa51-100) - LS-C81768 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CDKN3 / KAP Antibody (aa33-59, AP) - LS-C207138 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody (aa33-59, APC) - LS-C207139 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody (aa39-68) - LS-C157637 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CDKN3 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The CDKN3 antibody detected the CDKN3 protein (arrow).

Anti-CDKN3 / KAP Antibody (aa33-59, Biotin) - LS-C207140 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody (aa31-80) - LS-C198789 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from LOVO cells, using CDKN3 Antibody. The lane on the right was incubated with synthetic peptide.

Anti-CDKN3 / KAP Antibody (aa33-59, FITC) - LS-C207141 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody (aa33-59) - LS-C159963 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KAP Antibody western blot of Jurkat cell line lysates (35 ug/lane). The KAP antibody detected the KAP protein (arrow).

Anti-CDKN3 / KAP Antibody (clone 2D11) - LS-C173318 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN3.

Anti-CDKN3 / KAP Antibody (clone 2A5) - LS-C173319 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN3.

Anti-CDKN3 / KAP Antibody (aa33-59, PE) - LS-C207143 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody (aa33-59, Azide-free, HRP) - LS-C207142 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody - LS-C192732 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of mouse heart cell line, using CDKN3 antibody.

Anti-CDKN3 / KAP Antibody (aa183-212, AP) - LS-C208397 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDKN3 / KAP Antibody (clone 2H10) - LS-C173315 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN3.

Anti-CDKN3 / KAP Antibody (clone 4D8) - LS-C173326 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D8
Anti-CDKN3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CDKN3.
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