RAD53

Gene Symbol RAD53
Entrez Gene 855950
Alt Symbol LSD1, MEC2, SPK1
Species Yeast
Gene Type protein-coding
Description serine/threonine/tyrosine protein kinase RAD53
Other Description -
Swissprots Q6B1S1 P22216 D6W3L5
Accessions DAA11281 P22216 NM_001183967 NP_015172
Function Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. Seems to be involved in the phosphorylation of RPH1. {ECO:0000269|PubMed:10550056, ECO:0000269|PubMed:11809875, ECO:0000269|PubMed:15024067, ECO:0000269|PubMed:7958905, ECO:0000269|PubMed:8355715}.
Subcellular Location Nucleus {ECO:0000269|PubMed:8355715}.
Top Pathways Cell cycle - yeast, Meiosis - yeast

Serine/threonine-protein kinase RAD53 (RAD53), partial, Recombinant Protein - MBS1102230 from MyBioSource

Category Protein
Prices $1,020.00, $1,020.00, $1,250.00, $1,250.00, $1,550.00, $1,550.00, $2,005.00, $2,005.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Yeast
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