SLIT1

Gene Symbol	SLIT1
Entrez Gene	6585
Alt Symbol	MEGF4, SLIL1, SLIT-1, SLIT3
Species	Human
Gene Type	protein-coding
Description	slit homolog 1 (Drosophila)
Other Description	multiple EGF-like domains protein 4|multiple epidermal growth factor-like domains protein 4|slit homolog 1 protein
Swissprots	Q9UIL7 Q8WWZ2 Q5T0V1 O75093
Accessions	EAW49956 EAW49957 EAW49958 EAW49959 O75093 AB011537 BAA32465 AB017167 BAA35184 AY029183 AAK31796 BC028105 BC139909 BC146761 AAI46762 BC146851 AAI46852 CD671648 NM_003061 NP_003052
Function	Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000250}.
Tissue Specificity	Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney. {ECO:0000269|PubMed:9813312}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLIT1 Antibody Blocking Peptide - LS-E2395 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLIT1 Antibody Blocking Peptide - LS-E21503 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLIT3 Antibody Blocking Peptide - LS-E21504 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Slit3 Protein - H00006586-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SLIT1-Antibody-N-term-Blocking-peptide - BP13374a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Slit1, CF - 6514-SL-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Met1-Gln915, with a C-terminal 6-His tag

SLIT1 Blocking Peptide - 33R-3156 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLIT3 Blocking Peptide - 33R-7343 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLIT3 protein - 30R-3338 from Fitzgerald Category Protein Prices $1,095.00 Sizes 500 µg Source E.coli Species Human

Human Slit Homolog 1 Protein - abx069113 from Abbexa Category Protein Source E.coli Species Human

Human Slit Homolog 1 Protein - abx069116 from Abbexa Category Protein Source E.coli Species Human

Slit Homolog 1 (Slit1), Human - 20-8761 from ARP American Research Products Category Protein Prices $429.00 Sizes 50 µg Source E.coli Species Human

Slit Homolog 1 (Slit1), Human - 20-8762 from ARP American Research Products Category Protein Prices $429.00 Sizes 50 µg Source E.coli Species Human

Recombinant Human Slit1, His-tagged - SLIT1-19H from Creative Biomart Category Protein Source CHO Species Human

Recombinant Human SLIT1, His-tagged - SLIT1-524H from Creative Biomart Category Protein Source CHO Cells Species Human

Slit1 - PR15075-50 from Neuromics Category Protein Prices $315.00 Sizes 50 µg Species Chimpanzee, Human

Recombinant Slit Homolog 1 (Slit1) - RPD354Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Slit Homolog 1 (Slit1) - RPD354Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Slit Homolog 1 (Slit1) - RPD354Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Slit Homolog 1 (Slit1) - RPD354Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Slit Homolog 1 (Slit1) - RPD354Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Slit Homolog 1 (Slit1) - RPD354Ra02 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Slit Homolog 1 (Slit1) - RPD354Ra03 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Slit Homolog 1 (Slit1) - RPD354Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Slit Homolog 1 (Slit1) - RPD354Hu02 from Cloud-clone Category Protein Source E.coli Species Human

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